Brunner Emily, Levy Robert
Healtheast, St. Paul (EB); and Family Medicine and Community Health, University of Minnesota, Minneapolis, MN (RL).
J Addict Med. 2017 May/Jun;11(3):239-240. doi: 10.1097/ADM.0000000000000303.
: This case report describes the development of dependence to phenibut, a gamma-aminobutyric acid-receptor type B agonist, in a patient concurrently being treated with buprenorphine. The patient experienced withdrawal symptoms which were successfully treated with a phenobarbital taper based on a protocol to treat sedative use disorder. This case report provided an example of the development of a phenibut use disorder and also brought up a public health question of whether phenibut should therefore be officially classified and monitored.
本病例报告描述了一名正在接受丁丙诺啡治疗的患者对γ-氨基丁酸B型受体激动剂苯乙胺酪酸产生依赖的情况。患者出现了戒断症状,根据治疗镇静剂使用障碍的方案,通过逐渐减少苯巴比妥剂量成功进行了治疗。本病例报告提供了一个苯乙胺酪酸使用障碍发展的实例,同时也提出了一个公共卫生问题,即苯乙胺酪酸是否因此应被正式分类和监测。