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大气中 PCDD/Fs 和 dl-PCBs 暴露与人类寿命关系的初步研究。

Preliminary study of possible relationships between exposure to PCDD/Fs and dl-PCBs in ambient air and the length of life of people.

机构信息

Department of Environmental Health Risk Factors, School of Public Health in Bytom, Medical University of Silesia in Katowice (Poland), ul. Piekarska 18, 42-902 Bytom, Poland.

Department of Environmental Health, School of Public Health in Bytom, Medical University of Silesia in Katowice (Poland), ul. Piekarska 18, 42-902 Bytom, Poland.

出版信息

Sci Total Environ. 2017 Nov 15;598:129-134. doi: 10.1016/j.scitotenv.2017.03.289. Epub 2017 Apr 22.

DOI:10.1016/j.scitotenv.2017.03.289
PMID:28441591
Abstract

There is a lack of studies on the impact of very toxic and persistent organic compounds as polychlorinated dibenzodioxins (PCDDs), dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) on the population life expectancy. Preliminary studies on the relations between exposure to PCDD/Fs and dl-PCBs in ambient air and the length of life of residents of 12 cities (2 million people) in the Silesia province has been undertaken. The average length of life of inhabitants in 12 cities of Silesia province was calculated on the basis of register of deaths after excluding deaths caused by external causes and the concentration of PCDD/Fs and dl-PCBs were measured. The studies have shown that inhalation exposure to dioxins, furans and dl-PCBs could be an important factor which may shorten the life expectancy of the population. The results of preliminary studies indicate a strong correlation between the concentration of PCDD/Fs and dl-PCBs in the ambient air and the length of life of women. The conducted analysis of the regression shows that reduction of chlorinated persistent organic compounds of 10fg I-TEQ/m could extend life expectancy of women by approximately 4months (0.3years).

摘要

目前,关于非常有毒和持久性有机化合物(多氯二苯并对二恶英(PCDDs)、二苯并呋喃(PCDFs)和多氯联苯(PCBs))对人口预期寿命的影响的研究还很少。目前已经开展了初步研究,以探讨环境空气中 PCDD/Fs 和 dl-PCBs 暴露与 12 个城市(200 万人)居民寿命之间的关系。西里西亚省 12 个城市居民的平均寿命是根据排除了因外部原因导致的死亡人数后的死亡登记册计算的,并测量了 PCDD/Fs 和 dl-PCBs 的浓度。研究表明,吸入二恶英、呋喃和 dl-PCBs 可能是缩短人口预期寿命的一个重要因素。初步研究的结果表明,环境空气中 PCDD/Fs 和 dl-PCBs 的浓度与女性的寿命之间存在很强的相关性。对回归的分析表明,氯化持久性有机化合物减少 10fg I-TEQ/m 可使女性的预期寿命延长约 4 个月(0.3 年)。

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