Patil Renuka, Shimpi Apurv, Rairikar Savita, Shyam Ashok, Sancheti Parag
Department of Community Physiotherapy, Sancheti College of Physiotherapy, Pune, Maharashtra, India.
Research Department, Sancheti Institute of Orthopaedics and Rehabilitation, Pune, Maharashtra, India.
Indian J Sex Transm Dis AIDS. 2017 Jan-Jun;38(1):47-53. doi: 10.4103/0253-7184.196886.
Highly active antiretroviral therapy has significantly extended survival of human immunodeficiency virus (HIV) infected patients. These drugs suppress replication of HIV but at the same time, have many physical and mental side effects which may affect daily activities of the patients. The present study assessed if moderate intensity exercise program helped in enhancing the physical fitness and quality of life (QoL) in HIV positive females which may reduce the comorbidities associated with the disease and medications.
The aim of this study is to study the effects of moderate intensity physical training on physical fitness parameters and QoL in HIV positive females.
Post IEC approval, a randomized control, single-blinded, parallel group trial was conducted on 55 females (20 experimental HIV, 20 control HIV, 15 control normal) matching the selection criteria. Post informed consent, their muscular endurance, flexibility, aerobic capacity, and QoL was assessed. Moderate intensity physical exercises were given to experimental HIV and control normal 5 days/week for 8 weeks and subjects were reassessed for above parameters. Intragroup analysis was performed using paired -test while inter-group was by one-way ANOVA with alpha set at ≤0.05.
Moderate-intensity exercises improved muscular endurance ( < 0.05), flexibility ( < 0.05), and aerobic capacity ( < 0.05)in experimental HIV and control normal group as compared to control HIV group. QoL in experimental HIV showed improvement in all the domains.
Moderate-intensity exercises help improve the physical fitness as well as enhance the QoL in HIV positive females.
高效抗逆转录病毒疗法显著延长了人类免疫缺陷病毒（HIV）感染患者的生存期。这些药物可抑制HIV复制，但同时会产生许多身心副作用，可能影响患者的日常活动。本研究评估了中等强度运动计划是否有助于提高HIV阳性女性的身体素质和生活质量（QoL），这可能会降低与该疾病及药物相关的合并症。
本研究的目的是探讨中等强度体育锻炼对HIV阳性女性身体素质参数和生活质量的影响。
经独立伦理委员会（IEC）批准后，对55名符合入选标准的女性（20名实验性HIV患者、20名对照HIV患者、15名对照正常女性）进行了随机对照、单盲、平行组试验。在获得知情同意后，评估了她们的肌肉耐力、柔韧性、有氧能力和生活质量。对实验性HIV患者和对照正常女性每周进行5天、为期8周的中等强度体育锻炼，并对上述参数进行重新评估。组内分析采用配对t检验，组间分析采用单因素方差分析，设定α≤0.05。
与对照HIV组相比，中等强度运动改善了实验性HIV组和对照正常组的肌肉耐力（P<0.05）、柔韧性（P<0.05）和有氧能力（P<0.05）。实验性HIV组的生活质量在所有领域均有改善。
中等强度运动有助于提高HIV阳性女性的身体素质并提升其生活质量。
