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女童难治性尿失禁:膀胱颈的作用

Refractory Urinary Incontinence in Girls: The Role of the Bladder Neck.

作者信息

Chrzan Rafal

机构信息

Pediatric Urology, Jagiellonian University Medical College, Krakow, Poland.

出版信息

Front Pediatr. 2017 Apr 10;5:74. doi: 10.3389/fped.2017.00074. eCollection 2017.

Abstract

BACKGROUND

Prevalence of lower urinary tract dysfunction (LUTD) in children is between 6 and 9% with urinary incontinence (UI) being one of the most common symptom.

VARIOUS ASPECTS OF LOWER URINARY TRACT SYMPTOMS LUTS

Anatomical anomalies of the urinary tract as well as neurogenic underlying pathology can results in LUTS. Comorbidities and long-term consequences of the LUTD for the female patients as well as genetic issues are also briefly discussed.

THE ROLE OF THE BLADDER NECK

Thanks to urodynamics, we have learnt a lot about the lower urinary tract function, but the role of the bladder neck in the pathophysiology of LUTS in children is not clear. Secondary bladder neck hypertrophy is a well-described pathology, but there is no standardized treatment for this phenomenon. Primary bladder neck dysfunction has already been defined by the International Children's Continence Society.

REFRACTORY UI IN GIRLS

Uniform diagnostic protocols are used in these girls with UI. Treatment consists of standard urotherapy, additional interventions, and pharmacotherapy in selected cases. Those with refractory UI require careful reassessment to look for the unrecognized disorders. Invasive urodynamics should be done in those patients. Ultrasound of the bladder neck region and the pelvic floor can be helpful, but its interpretation is very subjective. In a small group bladder neck insufficiency can be found and those might benefit from a surgical intervention.

FUTURE PERSPECTIVE

Strict criteria of the bladder neck insufficiency in children must be defined. Early surgical intervention in girls with bladder neck insufficiency might reduce the long period of intensive conservative treatment.

摘要

背景

儿童下尿路功能障碍(LUTD)的患病率在6%至9%之间,尿失禁(UI)是最常见的症状之一。

下尿路症状(LUTS)的各个方面:尿路的解剖异常以及神经源性潜在病理状况可导致LUTS。还简要讨论了LUTD对女性患者的合并症、长期后果以及遗传问题。

膀胱颈的作用

借助尿动力学,我们对下尿路功能有了很多了解,但膀胱颈在儿童LUTS病理生理学中的作用尚不清楚。继发性膀胱颈肥大是一种已被充分描述的病理状况,但针对这一现象尚无标准化治疗方法。原发性膀胱颈功能障碍已由国际儿童尿控协会定义。

女童难治性尿失禁

对这些患有尿失禁的女童采用统一的诊断方案。治疗包括标准的尿疗、额外干预措施以及在特定病例中进行药物治疗。那些难治性尿失禁患者需要仔细重新评估以寻找未被识别的病症。这些患者应进行侵入性尿动力学检查。膀胱颈区域和盆底的超声检查可能会有帮助,但其解读非常主观。在一小部分患者中可发现膀胱颈功能不全,这些患者可能从手术干预中获益。

未来展望

必须定义儿童膀胱颈功能不全的严格标准。对膀胱颈功能不全的女童进行早期手术干预可能会减少长期的强化保守治疗时间。

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Refractory Urinary Incontinence in Girls: The Role of the Bladder Neck.女童难治性尿失禁:膀胱颈的作用
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