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3-Dimensional Facial Analysis-Facing Precision Public Health.

作者信息

Baynam Gareth, Bauskis Alicia, Pachter Nicholas, Schofield Lyn, Verhoef Hedwig, Palmer Richard L, Kung Stefanie, Helmholz Petra, Ridout Michael, Walker Caroline E, Hawkins Anne, Goldblatt Jack, Weeramanthri Tarun S, Dawkins Hugh J S, Molster Caron M

机构信息

Genetic Services of Western Australia, Department of Health, Government of Western Australia, Perth, WA, Australia.

Western Australian Register of Developmental Anomalies, Perth, WA, Australia.

出版信息

Front Public Health. 2017 Apr 10;5:31. doi: 10.3389/fpubh.2017.00031. eCollection 2017.

Abstract

Precision public health is a new field driven by technological advances that enable more precise descriptions and analyses of individuals and population groups, with a view to improving the overall health of populations. This promises to lead to more precise clinical and public health practices, across the continuum of prevention, screening, diagnosis, and treatment. A phenotype is the set of observable characteristics of an individual resulting from the interaction of a genotype with the environment. Precision (deep) phenotyping applies innovative technologies to exhaustively and more precisely examine the discrete components of a phenotype and goes beyond the information usually included in medical charts. This form of phenotyping is a critical component of more precise diagnostic capability and 3-dimensional facial analysis (3DFA) is a key technological enabler in this domain. In this paper, we examine the potential of 3DFA as a public health tool, by viewing it against the 10 essential public health services of the "public health wheel," developed by the US Centers for Disease Control. This provides an illustrative framework to gage current and emergent applications of genomic technologies for implementing precision public health.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c79/5385440/2a89af379f6c/fpubh-05-00031-g001.jpg

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