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优化公共卫生领域的精准医学

Optimizing Precision Medicine for Public Health.

作者信息

Bilkey Gemma A, Burns Belinda L, Coles Emily P, Mahede Trinity, Baynam Gareth, Nowak Kristen J

机构信息

Office of Population Health Genomics, Public and Aboriginal Health Division, Department of Health, Government of Western Australia, Perth, WA, Australia.

Office of the Chief Health Officer, Public and Aboriginal Health Division, Department of Health, Government of Western Australia, Perth, WA, Australia.

出版信息

Front Public Health. 2019 Mar 7;7:42. doi: 10.3389/fpubh.2019.00042. eCollection 2019.

DOI:10.3389/fpubh.2019.00042
PMID:30899755
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6416195/
Abstract

Advances in precision medicine have presented challenges to traditional public health decision-making paradigms. Historical methods of allocating healthcare funds based on safety, efficacy, and efficiency, are challenged in a healthcare delivery model that focuses on individualized variations in pathology that form the core of precision medicine. Public health policy and decision-making must adapt to this new frontier of healthcare delivery to ensure that the broad public health goals of reducing healthcare disparities and improving the health of populations are achieved, through effective and equitable allocation of healthcare funds. This paper discusses contemporary applications of precision medicine, and the potential impacts of these on public health policy and decision-making, with particular focus on patients living with rare diseases and rare cancers. The authors then reconcile these, presenting precision public health as the bridge between these seemingly competing fields.

摘要

精准医学的进展给传统公共卫生决策范式带来了挑战。在基于安全性、有效性和效率分配医疗保健资金的传统方法中,这种方法在专注于构成精准医学核心的病理学个体差异的医疗服务模式中受到了挑战。公共卫生政策和决策必须适应这一医疗服务的新前沿,以确保通过有效和公平地分配医疗保健资金,实现减少医疗保健差距和改善人群健康这一广泛的公共卫生目标。本文讨论了精准医学的当代应用,以及这些应用对公共卫生政策和决策的潜在影响,特别关注罕见病和罕见癌症患者。作者随后协调了这些问题,提出精准公共卫生是这些看似相互竞争的领域之间的桥梁。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe1f/6416195/c9489210d74c/fpubh-07-00042-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe1f/6416195/e3a82c9a052c/fpubh-07-00042-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe1f/6416195/c9489210d74c/fpubh-07-00042-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe1f/6416195/e3a82c9a052c/fpubh-07-00042-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe1f/6416195/c9489210d74c/fpubh-07-00042-g0002.jpg

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