Huynh Dieu T T, Tran Nga T, Nguyen Lam T, Berde Yatin, Low Yen Ling
a Abbott Nutrition Research and Development Asia-Pacific Center , Singapore.
b National Institution of Nutrition , Ha Noi , Vietnam.
J Matern Fetal Neonatal Med. 2018 Jun;31(12):1586-1594. doi: 10.1080/14767058.2017.1320984. Epub 2017 May 7.
This study aimed to evaluate the effects of maternal nutritional supplementation (MNS) in conjunction with a breastfeeding support program on birth outcomes and breastfeeding performance.
A total of 228 singleton Vietnamese mothers aged 20-35 years at 26-29 weeks of gestation with pre-pregnancy body mass index (BMI) < 25.0 kg/m were randomized to the intervention (n = 114), receiving MNS (252 kcal/day) daily up to 12 weeks postpartum and four breastfeeding education and support sessions or to the control (n = 114), receiving standards of care.
The intervention was 2.09 times more likely to exclusively breastfeed over the 12 weeks than the control (95%CI: 1.05-4.13, p = .0358), after controlling for potential confounders. Infant's breast milk intake was significantly higher in the intervention than the control among mothers with baseline mid-upper arm circumference (MUAC) < 50th (p = .0251). Infants in the intervention had significantly higher birth weight (p = .0312), birth weight-for-age (p = .0141) and birth head circumference-for-age (p = .0487), and higher head circumference-for-age z-score (p = .0183) development over the postnatal period, compared with the control.
Use of MNS and breastfeeding support improve birth outcomes and exclusive breastfeeding (EBF) rate in Vietnamese mothers. Additionally, it promotes breast milk production among mothers with lower baseline MUAC.
本研究旨在评估孕产妇营养补充(MNS)联合母乳喂养支持项目对分娩结局和母乳喂养情况的影响。
共有228名单胎越南母亲参与研究,她们在妊娠26 - 29周时年龄为20 - 35岁,孕前体重指数(BMI)< 25.0 kg/m²,被随机分为干预组(n = 114),从妊娠至产后12周每天接受MNS(252千卡/天)以及四次母乳喂养教育和支持课程;或对照组(n = 114),接受标准护理。
在控制潜在混杂因素后,干预组在12周内纯母乳喂养的可能性是对照组的2.09倍(95%置信区间:1.05 - 4.13,p = 0.0358)。在基线时上臂中部周长(MUAC)<第50百分位数的母亲中,干预组婴儿的母乳摄入量显著高于对照组(p = 0.0251)。与对照组相比,干预组婴儿出生体重(p = 0.0312)、出生体重/年龄(p = 0.0141)和出生头围/年龄(p = 0.0487)显著更高,且在出生后时期头围/年龄z评分(p = 0.0183)发育更好。
MNS和母乳喂养支持可改善越南母亲的分娩结局和纯母乳喂养(EBF)率。此外,它还能促进基线MUAC较低的母亲的母乳分泌。