Max-Planck-Institut für Intelligente Systeme, Heisenbergstraβe 3, 70569 Stuttgart, Germany.
Lab Chip. 2017 May 16;17(10):1761-1768. doi: 10.1039/c7lc00178a.
A variety of diagnostic and therapeutic medical technologies rely on long term implantation of an electronic device to monitor or regulate a patient's condition. One proposed approach to powering these devices is to use a biofuel cell to convert the chemical energy from blood nutrients into electrical current to supply the electronics. We present here an enzymatic microbiofuel cell whose electrodes are directly integrated into a digital electronic circuit. Glucose oxidizing and oxygen reducing enzymes are immobilized on microelectrodes of an application specific integrated circuit (ASIC) using redox hydrogels to produce an enzymatic biofuel cell, capable of harvesting electrical power from just a single droplet of 5 mM glucose solution. Optimisation of the fuel cell voltage and power to match the requirements of the electronics allow self-powered operation of the on-board digital circuitry. This study represents a step towards implantable self-powered electronic devices that gather their energy from physiological fluids.
各种诊断和治疗医疗技术都依赖于长期植入电子设备来监测或调节患者的状况。为这些设备供电的一种方法是使用生物燃料电池将血液营养物中的化学能转化为电流来为电子设备供电。我们在这里提出了一种酶促微生物燃料电池，其电极直接集成到数字电子电路中。使用氧化还原水凝胶将葡萄糖氧化酶和氧还原酶固定在专用集成电路（ASIC）的微电极上，以产生能够从 5mM 葡萄糖溶液的单个液滴中获取电能的酶促生物燃料电池。优化燃料电池的电压和功率以匹配电子设备的要求，从而允许板载数字电路的自供电操作。这项研究代表了朝着从生理液体中获取能量的可植入自供电电子设备迈出的一步。
