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妊娠期糖尿病高危孕妇的胰岛素敏感性及有氧运动后的血糖反应

Insulin Sensitivity and Plasma Glucose Response to Aerobic Exercise in Pregnant Women at Risk for Gestational Diabetes Mellitus.

作者信息

Embaby Heba, Elsayed Enas, Fawzy Mohamed

机构信息

Department of Physical Therapy, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, KSA.

Department of Physical Therapy for Obstetrics and Gynecology, Faculty of Physical Therapy, Cairo University.

出版信息

Ethiop J Health Sci. 2016 Sep;26(5):409-414. doi: 10.4314/ejhs.v26i5.2.

Abstract

BACKGROUND

Gestational diabetes mellitus (GDM) is one of the common complications that occur during pregnancy. Early intervention is essential to prevent the development of the disease in the non-pregnant state but also helpful in preventing the occurrence of GDM. The aim of the study was to assess the effect of aerobic exercises on insulin sensitivity and fasting plasma glucose level in pregnant women with risk for gestational diabetes mellitus.

MATERIALS AND METHODS

Forty multigravidae women between 20-24 weeks of gestation with risk for GDM were randomly selected (age range was 25-35 years), body mass index ranged from 30-35 kg/m. Women were divided into two equal groups: intervention group (A), which followed an aerobic exercise program in the form of walking on treadmill, three times weekly until the end of 37 weeks of gestation in addition to diet control. Control group (B) which received diet control with usual care given by obstetricians and midwives. Evaluation of the women in both groups was carried out before and after treatment program through assessment of fasting blood glucose and insulin levels.

RESULTS

There was a highly statistically significance decrease in fasting blood glucose level, fasting insulin level in both groups where the p value was 0.0001 favoring group (A).

CONCLUSION

Moderate intensity of aerobic exercises were effective in reducing fasting blood glucose level and fasting insulin level in pregnant women with risk for gestational diabetes mellitus.

摘要

背景

妊娠期糖尿病(GDM)是孕期常见并发症之一。早期干预对于预防非孕期疾病发展至关重要,同时也有助于预防GDM的发生。本研究旨在评估有氧运动对有妊娠期糖尿病风险的孕妇胰岛素敏感性和空腹血糖水平的影响。

材料与方法

随机选取40名妊娠20 - 24周、有GDM风险的经产妇(年龄范围25 - 35岁),体重指数为30 - 35kg/m 。将这些女性分为两组,每组人数相等:干预组(A组),除饮食控制外,以在跑步机上行走的形式进行有氧运动计划,每周三次,直至妊娠37周结束。对照组(B组)接受产科医生和助产士常规护理及饮食控制。通过评估空腹血糖和胰岛素水平,在治疗方案前后对两组女性进行评估。

结果

两组空腹血糖水平、空腹胰岛素水平均有高度统计学意义的下降,p值为0.0001,有利于A组。

结论

中等强度的有氧运动对降低有妊娠期糖尿病风险的孕妇空腹血糖水平和空腹胰岛素水平有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a126/5389055/7da5d31e1c8e/EJHS2605-0409Fig1.jpg

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