Beard Kristen, Swanström Lee L
Providence Portland Comprehensive Cancer Center, Portland, OR, USA.
Division of GI and MIS Surgery, The Oregon Clinic, Portland, OR, USA.
J Thorac Dis. 2017 Mar;9(Suppl 2):S154-S162. doi: 10.21037/jtd.2017.03.133.
Zenker's diverticula (ZDs) are a relatively common cause of cervical dysphagia. Diagnosis is best by a good upper GI exam though upper endoscopy should be performed as well. Treatment is either by open, transcervical approaches or trans-oral. Over the past 20 years, transoral approach has mostly replace transcervical approaches due to less pain, no scarring and a rapid recovery. Transoral approaches are either using rigid access or flexible endoscopy. Today, the most common approach is transoral stapling using a 12 mm laparoscopic linear cutting stapler. This has the drawbacks of requiring extreme neck extension, the massive size of the stapler making visualization mostly impossible and the current staple design that does not cut/staple all the way to the end of the blades-resulting in a residual pouch. Flexible endoscopy allows a more tailored approach under direct vision, the myotomy can even be extended beyond the diverticulum and onto the esophageal wall to minimize the risk of incomplete myotomy. Experienced endoscopists report high technical success and low complication. Success rates are similar but maybe slightly higher than with ridged transoral approaches or open surgery. Today, flexible endoscopic Zenkers is our preferred initial approach-with open or ridged being reserved for special indications.
Zenker憩室(ZD)是导致颈部吞咽困难的一个相对常见原因。最佳诊断方法是进行完善的上消化道检查,不过也应进行上消化道内镜检查。治疗方法包括开放性经颈入路或经口入路。在过去20年中,由于疼痛较轻、无瘢痕形成且恢复迅速,经口入路已大多取代了经颈入路。经口入路可采用硬质器械或软性内镜。如今,最常用的方法是使用12毫米腹腔镜线性切割吻合器进行经口吻合。这种方法存在一些缺点,如需要极度伸展颈部,吻合器尺寸过大几乎无法进行可视化操作,以及当前的吻合器设计无法一直切割/吻合到刀片末端,从而导致残留憩室。软性内镜可在直视下采用更具针对性的方法,肌切开术甚至可延伸至憩室以外并进入食管壁,以降低肌切开术不完全的风险。经验丰富的内镜医师报告称技术成功率高且并发症少。成功率相似,但可能略高于硬质经口入路或开放手术。如今,软性内镜下Zenker憩室手术是我们首选的初始治疗方法,开放手术或硬质器械手术则保留用于特殊情况。