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[关节内良性肿瘤的诊断与治疗]

[Diagnosis and therapy of benign intraarticular tumors].

作者信息

Dürr H R, Klein A

机构信息

Schwerpunkt Tumororthopädie, Klinik und Poliklinik für Orthopädie, Physikalische Medizin und Rehabilitation, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Deutschland.

出版信息

Orthopade. 2017 Jun;46(6):498-504. doi: 10.1007/s00132-017-3427-1.

DOI:10.1007/s00132-017-3427-1
PMID:28447110
Abstract

Intraarticular benign tumors are rare lesions in many cases seen as incidental findings. One of the typical lesions is the diffuse or nodular form of pigmented villonodular synovitis, which needs a complete surgical removal. Magnetic Resonance Imaging (MRI) is diagnostic in most of the cases because of the intracellular iron content which shows an at least in some parts dark T2-sequence. Adjuvant therapies as radiosynoviorthesis should be considered in diffuse or recurrent lesions. Synovial Chondromatosis represents a metaplastic disorder of the synovial membrane resulting in the production of loose cartilage bodies. Also in this dissease synovectomy or, in late cases, removal of the loose bodies only, is recommended. Synovial hemangiomas are hamartomas which may lead to pain or restriction of movement. In these cases total or partial resection is justified. Alternative treatment options such as laserablation may be possible. Lipoma arborescens represents a proliferative lipoid lesion of the subsynovial region leading to villonodular synovial proliferation. If clinically symptomatic, resection by arthroscopic or open synovectomy is recommented.

摘要

关节内良性肿瘤在很多情况下是罕见病变,多为偶然发现。典型病变之一是色素沉着绒毛结节性滑膜炎的弥漫性或结节性形式,需要完整手术切除。磁共振成像(MRI)在大多数病例中具有诊断价值,因为细胞内铁含量在至少部分区域表现为T2序列低信号。对于弥漫性或复发性病变,应考虑放射性滑膜切除等辅助治疗。滑膜软骨瘤病是滑膜的一种化生紊乱,导致产生游离软骨体。对于这种疾病,同样建议进行滑膜切除术,或在晚期仅切除游离体。滑膜血管瘤是错构瘤,可能导致疼痛或活动受限。在这些情况下,进行全部或部分切除是合理的。也可能有激光消融等替代治疗选择。树状脂肪瘤是滑膜下区域的一种增殖性类脂病变,导致绒毛结节性滑膜增生。如果有临床症状,建议通过关节镜或开放性滑膜切除术进行切除。

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[Diagnosis and therapy of benign intraarticular tumors].[关节内良性肿瘤的诊断与治疗]
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Diagnostic accuracy of synovial chondromatosis of the temporomandibular joint on magnetic resonance imaging.颞下颌关节滑膜软骨瘤病的磁共振成像诊断准确性。
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本文引用的文献

1
Imatinib mesylate induces mitochondria-dependent apoptosis and inhibits invasion of human pigmented villonodular synovitis fibroblast-like synovial cells.甲磺酸伊马替尼诱导人色素沉着绒毛结节性滑膜炎成纤维样滑膜细胞发生线粒体依赖性凋亡并抑制其侵袭。
Oncol Rep. 2016 Jan;35(1):197-204. doi: 10.3892/or.2015.4350. Epub 2015 Oct 26.
2
Synchronous Lipoma arborescens of bilateral wrist: An extremely rare manifestation and a new perspective on etiopathogenesis.
J Cancer Res Ther. 2015 Jul-Sep;11(3):646. doi: 10.4103/0973-1482.150402.
3
[Synovial tumors and tumor-like lesions].
Orthopade. 2015 Oct;44(10):823-34. doi: 10.1007/s00132-015-3162-4.
4
Synovial haemangioma of the knee: an under recognised condition.膝关节滑膜血管瘤:一种未被充分认识的病症。
Int Orthop. 2015 Oct;39(10):2037-40. doi: 10.1007/s00264-015-2930-4. Epub 2015 Jul 31.
5
CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study.依马妥珠单抗治疗局部晚期弥漫型腱鞘巨细胞瘤的剂量递增和扩展 1 期研究。
Lancet Oncol. 2015 Aug;16(8):949-56. doi: 10.1016/S1470-2045(15)00132-1. Epub 2015 Jul 12.
6
The effect of surgical synovectomy and radiotherapy on the rate of recurrence of pigmented villonodular synovitis of the knee: an individual patient meta-analysis.手术滑膜切除术和放射治疗对膝关节色素沉着绒毛结节性滑膜炎复发率的影响:一项个体患者荟萃分析。
Bone Joint J. 2015 Apr;97-B(4):550-7. doi: 10.1302/0301-620X.97B4.34907.
7
Lipoma arborescens of the knee.膝关节树枝状脂肪瘤
Knee Surg Sports Traumatol Arthrosc. 2015 Aug;23(8):2196-2201. doi: 10.1007/s00167-014-2996-3. Epub 2014 Apr 22.
8
Synovial chondrosarcoma arising in synovial chondromatosis.滑膜软骨瘤病中发生的滑膜软骨肉瘤。
Sarcoma. 2014;2014:647939. doi: 10.1155/2014/647939. Epub 2014 Mar 5.
9
Lipoma arborescens.树枝状脂肪瘤
Singapore Med J. 2014 Jan;55(1):5-10; quiz 11. doi: 10.11622/smedj.2014003.
10
A low recurrence rate is possible with a combination of surgery and radiosynovectomy for diffuse pigmented villonodular synovitis of the knee.对于膝关节弥漫性色素沉着绒毛结节性滑膜炎,采用手术联合放射性滑膜切除术可能会降低复发率。
Clin Nucl Med. 2013 Aug;38(8):608-15. doi: 10.1097/RLU.0b013e318292efdf.