Hsi E D
Department of Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA.
Int J Lab Hematol. 2017 May;39 Suppl 1:14-22. doi: 10.1111/ijlh.12650.
In the 8 years since the publication of the 4th edition of the WHO Classification of Hematopoietic and Lymphoid Tumours in 2008, there has been rapid accumulation of knowledge in the molecular genetics, biology, clinical behavior of many hematologic malignancies. Concepts and models have advanced to the point at which updates were deemed necessary prior to the formal WHO process of publication of a 5th edition as part of the WHO "blue book" series. This overview will focus on lymphoid tumors and highlight important changes and updates to these neoplasms.
自2008年《世界卫生组织造血与淋巴组织肿瘤分类》第4版出版后的8年里，许多血液系统恶性肿瘤在分子遗传学、生物学及临床行为方面的知识迅速积累。概念和模型已发展到这样的程度，即有必要在世界卫生组织作为“蓝皮书”系列正式出版第5版的流程之前进行更新。本综述将聚焦于淋巴肿瘤，并着重介绍这些肿瘤的重要变化和更新内容。
