Jürimäe Jaak, Võsoberg Kristel, Tamm Anna-Liisa, Maasalu Katre, Remmel Liina, Tillmann Vallo
a Institute of Sport Sciences and Physiotherapy, Faculty of Medicine, University of Tartu , Tartu , Estonia.
b Tartu Health Care College , Tartu , Estonia.
Eur J Sport Sci. 2017 Aug;17(7):867-873. doi: 10.1080/17461391.2017.1315177. Epub 2017 Apr 27.
Various inflammation parameters are increased with childhood obesity, but few comparable data are found in lean growing athletes. This study aims to characterize differences in 12 simultaneously measured inflammatory parameters between pubertal rhythmic gymnasts (RG) and untrained controls (UC), and to examine the relationship between body composition and inflammatory markers. Sixty 10-12-year-old girls were divided into RG (n = 30) and UC (n = 30). Fat mass (FM) and fat free mass (FFM) were measured by dual-energy X-ray absorptiometry. Leptin and 12 inflammatory parameters (interleukin [IL]-2, IL-4, IL-6, IL-8, IL-10, vascular endothelial growth factor, interferon-gamma [IFN-γ], tumor necrosis factor-alpha, IL-1α, IL-1β, monocyte chemotactic protein-1 and epidermal growth factor) were measured from fasting blood samples. No differences were seen in 12 inflammatory markers between studied groups. As expected, leptin (RG: 2.4 ± 1.1; UC: 7.6 ± 4.2 ng ml) and FM (RG: 7.3 ± 2.3; UC: 11.8 ± 5.1 kg) were lower (p < .05) in RG compared to UC. In the whole group of lean pubertal girls, 69.0% of the variability in body FM was determined by leptin, and 11.2% of the variability in body FFM was explained by IFN-γ. In conclusion, measured 12 inflammatory biomarkers were not different between RG and UC, despite lower leptin and FM in RG. In lean pubertal girls, IFN-γ was independently associated with FFM, and leptin with FM.
儿童肥胖会使多种炎症参数升高，但在身材瘦长的成长中的运动员中，类似的数据却很少见。本研究旨在描述青春期艺术体操运动员（RG）和未经训练的对照组（UC）之间同时测量的12种炎症参数的差异，并研究身体成分与炎症标志物之间的关系。60名10 - 12岁的女孩被分为RG组（n = 30）和UC组（n = 30）。通过双能X线吸收法测量脂肪量（FM）和去脂体重（FFM）。从空腹血样中测量瘦素和12种炎症参数（白细胞介素[IL]-2、IL-4、IL-6、IL-8、IL-10、血管内皮生长因子、干扰素-γ[IFN-γ]、肿瘤坏死因子-α、IL-1α、IL-1β、单核细胞趋化蛋白-1和表皮生长因子）。研究组之间的12种炎症标志物没有差异。正如预期的那样，与UC组相比，RG组的瘦素（RG：2.4±1.1；UC：7.6±4.2 ng/ml）和FM（RG：7.3±2.3；UC：11.8±5.1 kg）较低（p < 0.05）。在整个青春期瘦女孩组中，身体FM的69.0%的变异性由瘦素决定，身体FFM的11.2%的变异性由IFN-γ解释。总之，尽管RG组的瘦素和FM较低，但RG组和UC组之间测量的12种炎症生物标志物没有差异。在青春期瘦女孩中，IFN-γ与FFM独立相关，瘦素与FM独立相关。
