• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Real-time imaging of single neuronal cell apoptosis in patients with glaucoma.

作者信息

Cordeiro Maria F, Normando Eduardo M, Cardoso M Jorge, Miodragovic Serge, Jeylani Seham, Davis Benjamin M, Guo Li, Ourselin Sebastien, A'Hern Roger, Bloom Philip A

机构信息

Glaucoma and Retinal Neurodegeneration Group, Department of Visual Neuroscience, UCL Institute of Ophthalmology, London EC1V 9EL, UK.

The Western Eye Hospital, Imperial College Healthcare NHS Trust (ICHNT), London NW1 5QH, UK.

出版信息

Brain. 2017 Jun 1;140(6):1757-1767. doi: 10.1093/brain/awx088.

DOI:10.1093/brain/awx088
PMID:28449038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5445254/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/473f/5445254/8e132c045ff6/awx088f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/473f/5445254/5e7f2879245a/awx088f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/473f/5445254/0cd2c7e43122/awx088f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/473f/5445254/8e132c045ff6/awx088f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/473f/5445254/5e7f2879245a/awx088f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/473f/5445254/0cd2c7e43122/awx088f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/473f/5445254/8e132c045ff6/awx088f3.jpg

相似文献

1
Real-time imaging of single neuronal cell apoptosis in patients with glaucoma.青光眼患者单个神经元细胞凋亡的实时成像
Brain. 2017 Jun 1;140(6):1757-1767. doi: 10.1093/brain/awx088.
2
Annexins in Glaucoma. annexins 在青光眼。
Int J Mol Sci. 2018 Apr 17;19(4):1218. doi: 10.3390/ijms19041218.
3
Increased production of tumor necrosis factor-alpha by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cells.暴露于模拟缺血或升高的静水压力下的神经胶质细胞产生更多的肿瘤坏死因子-α，可诱导共培养的视网膜神经节细胞发生凋亡。
J Neurosci. 2000 Dec 1;20(23):8693-700. doi: 10.1523/JNEUROSCI.20-23-08693.2000.
4
Biolistic Labeling of Retinal Ganglion Cells.视网膜神经节细胞的生物弹道标记法
Methods Mol Biol. 2018;1695:161-170. doi: 10.1007/978-1-4939-7407-8_14.
5
Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model.在体内青光眼模型中，使用细胞穿透性、可激活的肽探针进行视网膜神经节细胞凋亡的单细胞成像。
Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9391-6. doi: 10.1073/pnas.0812884106. Epub 2009 May 20.
6
[New perspectives in retinal imaging with OCT angiography].[光学相干断层扫描血管造影在视网膜成像中的新视角]
Ophthalmologe. 2016 Jan;113(1):4-5. doi: 10.1007/s00347-015-0193-5.
7
[New options of high resolution optical coherence tomography in glaucoma diagnostic].[青光眼诊断中高分辨率光学相干断层扫描的新选择]
Ophthalmologe. 2009 Aug;106(8):702-4, 706-8. doi: 10.1007/s00347-009-1999-9.
8
Imaging of retinal ganglion cells in glaucoma: pitfalls and challenges.青光眼的视网膜神经节细胞成像：陷阱与挑战。
Cell Tissue Res. 2013 Aug;353(2):261-8. doi: 10.1007/s00441-013-1600-3. Epub 2013 Mar 20.
9
[OCT Angiography of the Glaucoma Optic Nerve].[青光眼视神经的光学相干断层扫描血管造影]
Klin Monbl Augenheilkd. 2018 Feb;235(2):205-211. doi: 10.1055/s-0042-123830. Epub 2017 Mar 10.
10
A mouse retinal explant model for use in studying neuroprotection in glaucoma.一种用于研究青光眼神经保护作用的小鼠视网膜外植体模型。
Exp Eye Res. 2016 Oct;151:38-44. doi: 10.1016/j.exer.2016.07.010. Epub 2016 Jul 21.

引用本文的文献

1
Annexin-V binds subpopulation of immune cells altering its interpretation as an biomarker for apoptosis in the retina.膜联蛋白V结合免疫细胞亚群，改变了其作为视网膜细胞凋亡生物标志物的解读。
Int J Biol Sci. 2024 Nov 11;20(15):6073-6089. doi: 10.7150/ijbs.102551. eCollection 2024.
2
Translational Research and Therapies for Neuroprotection and Regeneration of the Optic Nerve and Retina: A Narrative Review.神经保护和视神经及视网膜再生的转化研究与治疗：叙述性综述。
Int J Mol Sci. 2024 Sep 29;25(19):10485. doi: 10.3390/ijms251910485.
3
New Therapeutic Strategies in Retinal Vascular Diseases: A Lipid Target, Phosphatidylserine, and Annexin A5-A Future Theranostic Pairing in Ophthalmology.

本文引用的文献

1
The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson's disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain.视网膜作为帕金森病鱼藤酮诱导模型中神经退行性变的早期生物标志物：罗格列酮对眼睛和大脑的神经保护作用的证据。
Acta Neuropathol Commun. 2016 Aug 18;4(1):86. doi: 10.1186/s40478-016-0346-z.
2
Estimating the rate of retinal ganglion cell loss to detect glaucoma progression: An observational cohort study.估计视网膜神经节细胞丢失率以检测青光眼进展：一项观察性队列研究。
Medicine (Baltimore). 2016 Jul;95(30):e4209. doi: 10.1097/MD.0000000000004209.
3
Risk of Visual Field Progression in Glaucoma Patients with Progressive Retinal Nerve Fiber Layer Thinning: A 5-Year Prospective Study.
视网膜血管疾病的新治疗策略：脂质靶点、磷脂酰丝氨酸和膜联蛋白A5——眼科未来的治疗诊断组合
Pharmaceuticals (Basel). 2024 Jul 24;17(8):979. doi: 10.3390/ph17080979.
4
Neuroretinal Cell Culture Model as a Tool for the Development of New Therapeutic Approaches for Oxidative Stress-Induced Ocular Diseases, with a Focus on Glaucoma.神经视网膜细胞培养模型作为一种开发氧化应激诱导的眼部疾病（重点是青光眼）新治疗方法的工具。
Cells. 2024 May 1;13(9):775. doi: 10.3390/cells13090775.
5
Immune Analysis Using Vitreous Optical Coherence Tomography Imaging in Rats with Steroid-Induced Glaucoma.使用玻璃体光学相干断层扫描成像对类固醇诱导性青光眼大鼠进行免疫分析
Biomedicines. 2024 Mar 13;12(3):633. doi: 10.3390/biomedicines12030633.
6
A time window for rescuing dying retinal ganglion cells.挽救濒死视网膜神经节细胞的时间窗。
Cell Commun Signal. 2024 Jan 31;22(1):88. doi: 10.1186/s12964-023-01427-3.
7
Real-Time Imaging of Single Retinal Cell Apoptosis in a Non-Human Primate Ocular Hypertension Model.实时成像在非人类灵长类动物眼高压模型中单视网膜细胞凋亡。
Transl Vis Sci Technol. 2024 Jan 2;13(1):20. doi: 10.1167/tvst.13.1.20.
8
Inhibition of ferroptosis promotes retina ganglion cell survival in experimental optic neuropathies.抑制铁死亡可促进实验性视神经病变中的视网膜神经节细胞存活。
Redox Biol. 2022 Dec;58:102541. doi: 10.1016/j.redox.2022.102541. Epub 2022 Nov 15.
9
Neuroprotection in neurodegenerations of the brain and eye: Lessons from the past and directions for the future.大脑和眼部神经退行性疾病中的神经保护：过去的经验与未来的方向
Front Neurol. 2022 Aug 12;13:964197. doi: 10.3389/fneur.2022.964197. eCollection 2022.
10
Evidence of an Annexin A4 mediated plasma membrane repair response to biomechanical strain associated with glaucoma pathogenesis.生物力学应变相关的青光眼发病机制中，膜联蛋白 A4 介导的质膜修复反应的证据。
J Cell Physiol. 2022 Sep;237(9):3687-3702. doi: 10.1002/jcp.30834. Epub 2022 Jul 21.
青光眼患者视网膜神经纤维层进行性变薄的视野进展风险：一项 5 年前瞻性研究。
Ophthalmology. 2016 Jun;123(6):1201-10. doi: 10.1016/j.ophtha.2016.02.017. Epub 2016 Mar 19.
4
Global image registration using a symmetric block-matching approach.使用对称块匹配方法的全局图像配准
J Med Imaging (Bellingham). 2014 Jul;1(2):024003. doi: 10.1117/1.JMI.1.2.024003. Epub 2014 Sep 19.
5
Progression of visual field in patients with primary open-angle glaucoma - ProgF study 1.原发性开角型青光眼患者视野进展 - ProgF研究1
Acta Ophthalmol. 2015 Dec;93(8):e615-20. doi: 10.1111/aos.12788. Epub 2015 Jun 12.
6
Preclinical validation of 99mTc-annexin A5-128 in experimental autoimmune myocarditis and infective endocarditis: comparison with 99mTc-HYNIC-annexin A5.99mTc-膜联蛋白A5-128在实验性自身免疫性心肌炎和感染性心内膜炎中的临床前验证：与99mTc-HYNIC-膜联蛋白A5的比较
Mol Imaging. 2014;13. doi: 10.2310/7290.2014.00049.
7
Direct optic nerve sheath (DONS) application of Schwann cells prolongs retinal ganglion cell survival in vivo.在体内，将施万细胞直接应用于视神经鞘可延长视网膜神经节细胞的存活时间。
Cell Death Dis. 2014 Oct 16;5(10):e1460. doi: 10.1038/cddis.2014.399.
8
Effect of the Aβ aggregation modulator MRZ-99030 on retinal damage in an animal model of glaucoma.Aβ聚集调节剂MRZ-99030对青光眼动物模型视网膜损伤的影响。
Neurotox Res. 2014 Nov;26(4):440-6. doi: 10.1007/s12640-014-9488-6. Epub 2014 Aug 9.
9
Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis.全球青光眼患病率及 2040 年青光眼负担预测：系统评价和荟萃分析。
Ophthalmology. 2014 Nov;121(11):2081-90. doi: 10.1016/j.ophtha.2014.05.013. Epub 2014 Jun 26.
10
Unexpected low-dose toxicity of the universal solvent DMSO.意想不到的通用溶剂 DMSO 的低剂量毒性。
FASEB J. 2014 Mar;28(3):1317-30. doi: 10.1096/fj.13-235440. Epub 2013 Dec 10.