Senin T, Franz M, Deuschle M, Bergemann N, Kammerer-Ciernioch J, Lautenschlager M, Meyer T
Integrative Rehabilitation Research Unit, Institute on Epidemiology, Social Medicine and Health Systems Research, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Vitos Klinikum Giessen-Marburg, Licherstraße 106, 35394, Giessen, Germany.
BMC Psychiatry. 2017 Apr 27;17(1):149. doi: 10.1186/s12888-017-1307-1.
There is a need for useful standardized Quality of Life (QoL) measures for people diagnosed with schizophrenia. Therefore, a short form of the self-administered Quality of Life in Schizophrenia (QLiS) scale was developed and validated.
Four steps were taken to develop the abridged version using samples from the Clinical Analysis of the Treatment of Schizophrenia (CATS) study. Firstly, a model with second order scales was developed using exploratory factor analysis (EFA). Secondly, it was tested in an independent sample using confirmatory factor analysis (CFA). Thirdly, this model served as the basis for selecting items for the short form. Distributional properties, content reviews, and factor loadings were taken into account in this step. Fourthly, the resulting short form was validated through confirmatory factor analysis (CFA). Composite reliability scores were calculated for the new subscales.
Three second order scales were constructed: illness-related quality of life (QoL), social life and finances, and global subjective well-being. CFA of the new theoretical model resulted in a CFI of 0.67 and absolute fit indices of CMIN/df = 2.55, RMSEA = 0.08, SRMR = 0.09. The selected 13 items showed good statistical properties and good fit of content to subscale. Fit of the underlying theoretical model with the reduced number of items was tested in an independent sample. Absolute and fit indices of the short form model were satisfactory (CFI = 0.95, CMIN/df = 2.23, RMSEA = 0.06, SRMR = 0.04). Composite reliability scores for three subscales were above 0.70.
The short form of the QLIS (QLiS-SF) showed good model fit and reliability. It should only be considered for use if the application of the long version is not suitable.
对于被诊断为精神分裂症的患者，需要实用的标准化生活质量（QoL）测量方法。因此，开发并验证了精神分裂症自我管理生活质量（QLiS）量表的简版。
采用精神分裂症治疗临床分析（CATS）研究中的样本，分四个步骤开发该删节版。首先，使用探索性因素分析（EFA）开发一个具有二阶量表的模型。其次，在一个独立样本中使用验证性因素分析（CFA）对其进行测试。第三，该模型作为选择简版项目的基础。此步骤中考虑了分布特性、内容审查和因素负荷。第四，通过验证性因素分析（CFA）对所得简版进行验证。计算新子量表的组合信度分数。
构建了三个二阶量表：疾病相关生活质量（QoL）、社会生活和财务状况以及总体主观幸福感。新理论模型的CFA得出CFI为0.67，绝对拟合指数为CMIN/df = 2.55，RMSEA = 0.08，SRMR = 0.09。所选的13个项目显示出良好的统计特性以及内容与子量表的良好契合度。在一个独立样本中测试了项目数量减少后的基础理论模型的拟合度。简版模型的绝对拟合指数和拟合度均令人满意（CFI = 0.95，CMIN/df = 2.23，RMSEA = 0.06，SRMR = 0.04）。三个子量表的组合信度分数均高于0.70。
QLIS简版（QLiS-SF）显示出良好的模型拟合度和信度。仅在不适合应用长版的情况下才应考虑使用它。
