Akpinar Guleser, Duman Ali, Gulen Bedia, Kapci Mucahit, Altinbilek Ertugrul, Ikizceli Ibrahim
Sisli Hamidiye Etfal Training and Research Hospital, Department of Emergency Medicine, Istanbul, Turkey.
Adnan Menderes University Hospital, Department of Emergency Medicine, Aydin, Turkey.
Pan Afr Med J. 2017 Jan 24;26:36. doi: 10.11604/pamj.2017.26.36.8746. eCollection 2017.
Cardiac injury resulting from blunt thoracic trauma is a frequent clinical occurrence which is difficult to diagnose. Our purpose in this study was to research whether H-FABP, which is a new marker for the diagnosis of cardiac injury, can be used in this patient group.
50 patients with blunt thoracic injury who were admitted to our emergency service within a period of 8 months and 50 cases as controls were included in our study.
Of the 50 patients with blunt thoracic injury in our study, 88% were male while 12% were female. The average age of the patients was 43 ± 15.15. While 27 (54%) of the 50 patients with blunt thoracic injury had cardiac injury, 23 (46%) did not have cardiac injury. The results of the statistical analyses showed a significant association between thorax trauma and cTnI, CPK, CPKMB and H-FABP (p<0.05). While there was a significant association between cardiac injury resulting from thoracic trauma and cTnI, ECG and TTE (p<0.05), there was no significant association between CPK, CPKMB and H-FABP (p>0.05).
In thoracic traumas, cardiac injury diagnosis can be made as a result of the assessment with Troponin-I, ECG and ECHO. For cardiac injury diagnosis, wide scale prospective studies are needed for H-FABP use.
钝性胸部创伤导致的心脏损伤是临床常见情况,难以诊断。本研究的目的是探究新型心脏损伤诊断标志物H-FABP是否可用于该患者群体。
本研究纳入了8个月内入住我院急诊科的50例钝性胸部损伤患者,并选取50例作为对照。
本研究中的50例钝性胸部损伤患者中,88%为男性,12%为女性。患者的平均年龄为43±15.15岁。50例钝性胸部损伤患者中,27例(54%)有心脏损伤,23例(46%)无心脏损伤。统计分析结果显示,胸部创伤与肌钙蛋白I(cTnI)、肌酸磷酸激酶(CPK)、肌酸磷酸激酶同工酶(CPKMB)和H-FABP之间存在显著相关性(p<0.05)。胸部创伤导致的心脏损伤与cTnI、心电图(ECG)和经胸超声心动图(TTE)之间存在显著相关性(p<0.05),而CPK、CPKMB与H-FABP之间无显著相关性(p>0.05)。
在胸部创伤中,可通过肌钙蛋白I、心电图和超声心动图评估进行心脏损伤诊断。对于心脏损伤诊断,H-FABP的应用需要大规模前瞻性研究。