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获得性免疫缺陷综合征的监测定义及1型人类免疫缺陷病毒感染的临床分类。

The surveillance definition of the acquired immunodeficiency syndrome and the clinical classification of infection with the human immunodeficiency virus type 1.

作者信息

Whyte B M, Cooper D A

机构信息

NHMRC Special Unit in AIDS Epidemiology and Clinical Research, University of New South Wales.

出版信息

Med J Aust. 1988 Oct 3;149(7):368-73. doi: 10.5694/j.1326-5377.1988.tb120671.x.

DOI:10.5694/j.1326-5377.1988.tb120671.x
PMID:2845235
Abstract

In 1982, one year after the first cases of the acquired immunodeficiency syndrome (AIDS) were reported, a case definition of AIDS was produced by the Centers for Disease Control, Atlanta, Georgia, USA. This definition was implemented world-wide, and it allowed the standardization of the reporting of cases. The identification of the virus that is responsible for AIDS, which subsequently was named the human immunodeficiency virus type 1 (HIV-1), led to the development of laboratory test procedures to detect its presence. The use of these tests confirmed that additional clinical manifestations were associated with severe outcomes of HIV-1 infection, which resulted in an increase in the number of conditions that were encompassed by AIDS. Moreover, the diagnosis of many AIDS-defining conditions could be made presumptively in the presence of proved HIV-1 infection. Thus the case definition required revision in 1985, and again in 1987. In addition, clinical expressions other than AIDS definitively were attributed to infection with HIV-1 after the widespread use of the testing procedures. The case definition of AIDS, as revised by the Centers for Disease Control in 1987, now is the current definition that is used in Australia. The clinical classification of HIV infection, which was produced by the Centers for Disease Control in 1986, was implemented in this country in January 1988.

摘要

1982年,在首例获得性免疫缺陷综合征(艾滋病)病例报告一年后,美国佐治亚州亚特兰大市疾病控制中心制定了艾滋病病例定义。该定义在全球范围内实施,使病例报告得以标准化。导致艾滋病的病毒被确定后,该病毒随后被命名为人类免疫缺陷病毒1型(HIV-1),这促使了检测其存在的实验室检测程序的发展。这些检测的应用证实,其他临床表现与HIV-1感染的严重后果相关,这导致艾滋病所涵盖的病症数量增加。此外,在确诊HIV-1感染的情况下,许多艾滋病界定病症可以初步诊断。因此,病例定义在1985年以及1987年需要修订。此外,在检测程序广泛应用后,除艾滋病之外的其他临床症状也明确归因于HIV-1感染。疾病控制中心于1987年修订的艾滋病病例定义,如今是澳大利亚使用的现行定义。疾病控制中心于1986年制定的HIV感染临床分类于1988年1月在该国实施。

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