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Through translational prospective study, the GSTP1 Ile105Val polymorphism emerges as prognostic marker in de novo large B-cell lymphoma patients.

作者信息

Delamain M T, Miranda E C M, Lourenço G J, de Souza C A, Lima C S P

机构信息

Hematology and Hemotherapy Center, University of Campinas, Sao Paulo, Brazil.

Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Sao Paulo, Brazil.

出版信息

Blood Cancer J. 2017 Apr 28;7(4):e560. doi: 10.1038/bcj.2017.38.

DOI:10.1038/bcj.2017.38
PMID:28452985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5436081/
Abstract
摘要

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本文引用的文献

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Predictive potential role of glutathione S-transferases polymorphisms in response to chemotherapy and breast cancer prognosis.谷胱甘肽S-转移酶基因多态性在化疗反应及乳腺癌预后中的预测潜在作用
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Pharmacogenetic association between GSTP1 genetic polymorphism and febrile neutropenia in Japanese patients with early breast cancer.日本早期乳腺癌患者中谷胱甘肽S-转移酶P1（GSTP1）基因多态性与发热性中性粒细胞减少症之间的药物遗传学关联
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Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab.免疫调节蛋白和代谢酶编码基因多态性对利妥昔单抗治疗弥漫性大 B 细胞淋巴瘤患者的易感性和结局的影响。
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Gene polymorphisms in cyclophosphamide metabolism pathway,treatment-related toxicity, and disease-free survival in SWOG 8897 clinical trial for breast cancer.环磷酰胺代谢途径中的基因多态性、治疗相关毒性与 SWOG8897 乳腺癌临床试验中的无病生存
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Glutathione-S-transferase genotypes influence the risk of chemotherapy-related toxicities and prognosis in Korean patients with diffuse large B-cell lymphoma.谷胱甘肽-S-转移酶基因型影响韩国弥漫性大B细胞淋巴瘤患者化疗相关毒性的风险及预后。
Cancer Genet Cytogenet. 2010 Apr 1;198(1):40-6. doi: 10.1016/j.cancergencyto.2009.12.004.
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Pharmacogenomics. 2009 Dec;10(12):1897-903. doi: 10.2217/pgs.09.134.
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Pharmacogenetic study in Hodgkin lymphomas reveals the impact of UGT1A1 polymorphisms on patient prognosis.
Blood. 2009 Apr 2;113(14):3307-13. doi: 10.1182/blood-2008-03-148874. Epub 2008 Sep 3.
9
Glutathione-S-transferase genotypes influence prognosis in follicular non-Hodgkin's Lymphoma.谷胱甘肽-S-转移酶基因型影响滤泡性非霍奇金淋巴瘤的预后。
Leuk Lymphoma. 2007 Mar;48(3):564-9. doi: 10.1080/10428190601158647.
10
The revised International Prognostic Index (R-IPI) is a better predictor of outcome than the standard IPI for patients with diffuse large B-cell lymphoma treated with R-CHOP.对于接受R-CHOP治疗的弥漫性大B细胞淋巴瘤患者，修订后的国际预后指数（R-IPI）比标准IPI能更好地预测预后。
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