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Immunogenicity and safety of three aluminium hydroxide adjuvanted vaccines with reduced doses of inactivated polio vaccine (IPV-Al) compared with standard IPV in young infants in the Dominican Republic: a phase 2, non-inferiority, observer-blinded, randomised, and controlled dose investigation trial.在多米尼加共和国的幼儿中,三种氢氧化铝佐剂灭活脊髓灰质炎疫苗(IPV-Al)与标准IPV相比,剂量降低后的免疫原性和安全性:一项2期、非劣效性、观察者盲法、随机和对照剂量研究试验。
Lancet Infect Dis. 2017 Jul;17(7):745-753. doi: 10.1016/S1473-3099(17)30177-9. Epub 2017 Apr 25.
2
Vaccine-induced mucosal immunity to poliovirus: analysis of cohorts from an open-label, randomised controlled trial in Latin American infants.疫苗诱导的针对脊髓灰质炎病毒的黏膜免疫:对拉丁美洲婴儿一项开放标签随机对照试验队列的分析
Lancet Infect Dis. 2016 Dec;16(12):1377-1384. doi: 10.1016/S1473-3099(16)30169-4. Epub 2016 Sep 13.
3
Fractional-Dose Inactivated Poliovirus Vaccine Immunization Campaign - Telangana State, India, June 2016.2016 年 6 月,印度特伦甘纳邦开展了口服脊髓灰质炎疫苗(减毒)分剂次免疫接种活动。
MMWR Morb Mortal Wkly Rep. 2016 Aug 26;65(33):859-63. doi: 10.15585/mmwr.mm6533a5.
4
Humoral and intestinal immunity induced by new schedules of bivalent oral poliovirus vaccine and one or two doses of inactivated poliovirus vaccine in Latin American infants: an open-label randomised controlled trial.新双价口服脊髓灰质炎疫苗免疫程序和一剂或两剂灭活脊髓灰质炎疫苗在拉丁美洲婴儿中诱导的体液和肠道免疫:一项开放标签随机对照试验。
Lancet. 2016 Jul 9;388(10040):158-69. doi: 10.1016/S0140-6736(16)00703-0. Epub 2016 May 19.
5
Immunogenicity and safety of a novel monovalent high-dose inactivated poliovirus type 2 vaccine in infants: a comparative, observer-blind, randomised, controlled trial.新型单价高剂量2型灭活脊髓灰质炎疫苗在婴儿中的免疫原性和安全性:一项比较、观察者盲法、随机、对照试验
Lancet Infect Dis. 2016 Mar;16(3):321-30. doi: 10.1016/S1473-3099(15)00488-0. Epub 2015 Dec 21.
6
Inactivated poliovirus vaccine given alone or in a sequential schedule with bivalent oral poliovirus vaccine in Chilean infants: a randomised, controlled, open-label, phase 4, non-inferiority study.在智利婴儿中单独使用或与二价口服脊髓灰质炎疫苗序贯使用灭活脊髓灰质炎病毒疫苗:一项随机、对照、开放性标签、四期、非劣效性研究。
Lancet Infect Dis. 2015 Nov;15(11):1273-82. doi: 10.1016/S1473-3099(15)00219-4. Epub 2015 Aug 26.
7
Polio eradication. Efficacy of inactivated poliovirus vaccine in India.脊髓灰质炎(小儿麻痹症)消除。印度灭活脊髓灰质炎病毒疫苗的效力。
Science. 2014 Aug 22;345(6199):922-5. doi: 10.1126/science.1255006.
8
Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised controlled trial.单剂灭活脊灰疫苗对先前口服脊灰疫苗儿童肠道脊灰病毒免疫力的影响:一项开放标签、随机对照试验。
Lancet. 2014 Oct 25;384(9953):1505-12. doi: 10.1016/S0140-6736(14)60934-X. Epub 2014 Jul 10.
9
Poliovirus vaccination options for achieving eradication and securing the endgame.脊灰病毒疫苗接种选项,以实现根除并确保终局之战。
Curr Opin Virol. 2013 Jun;3(3):309-15. doi: 10.1016/j.coviro.2013.05.007. Epub 2013 Jun 10.
10
Systematic review of mucosal immunity induced by oral and inactivated poliovirus vaccines against virus shedding following oral poliovirus challenge.口服及灭活脊髓灰质炎疫苗诱导黏膜免疫对口服脊髓灰质炎病毒攻击后病毒脱落的影响:系统评价
PLoS Pathog. 2012;8(4):e1002599. doi: 10.1371/journal.ppat.1002599. Epub 2012 Apr 19.

Maximising the impact of inactivated polio vaccines.

作者信息

Brickley Elizabeth B, Wright Peter F

机构信息

Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.

Department of Pediatrics, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

出版信息

Lancet Infect Dis. 2017 Jul;17(7):680-681. doi: 10.1016/S1473-3099(17)30236-0. Epub 2017 Apr 25.

DOI:10.1016/S1473-3099(17)30236-0
PMID:28454675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6047357/
Abstract
摘要