Kim Esther S, Omura Paige M C, Lo Andrew W
MIT Laboratory for Financial Engineering, Sloan School of Management, Cambridge, MA, USA; MIT Technology and Policy Program, Cambridge, MA, USA.
MIT Laboratory for Financial Engineering, Sloan School of Management, Cambridge, MA, USA; MIT Department of Chemical Engineering, Cambridge, MA, USA.
Drug Discov Today. 2017 Jul;22(7):1064-1068. doi: 10.1016/j.drudis.2017.03.015. Epub 2017 Apr 26.
Translating academic medical research into new therapies is an important challenge for the biopharmaceutical industry and investment communities, which have historically favored later-stage assets with lower risk and clearer commercial value. The Stanford SPARK program is an innovative model for addressing this challenge. The program was created in 2006 to educate students and faculty about bringing academic research from bench to bedside. Every year, the program provides mentorship and funding for approximately a dozen SPARK 'scholars,' with a focus on impacting patient lives, regardless of economic factors. By reviewing the detailed structure, function and operation of SPARK we hope to provide a template for other universities and institutions interested in de-risking and facilitating the translation of biomedical research.
将学术医学研究转化为新疗法，对生物制药行业和投资界来说是一项重大挑战，因为它们历来青睐风险较低、商业价值更明确的后期资产。斯坦福大学的SPARK项目是应对这一挑战的创新模式。该项目创建于2006年，旨在教育学生和教师如何将学术研究从实验室应用到临床。每年，该项目都会为大约十几名SPARK“学者”提供指导和资金，重点是改善患者生活，而不考虑经济因素。通过审视SPARK的详细结构、功能和运作，我们希望为其他有意降低生物医学研究风险并促进其转化的大学和机构提供一个模板。
