[通过原位杂交技术对巨细胞病毒进行选择性检测]
[Selective detection of cytomegalovirus by in situ hybridization].
作者信息
Cremer U
机构信息
Abteilung Rechtsmedizin der Medizinischen Fakultät, Rheinisch-Westfälische Technische Hochschule Aachen, Bundesrepublik Deutschland.
出版信息
Z Rechtsmed. 1988;100(4):237-42. doi: 10.1007/BF00201159.
PMID:2845686
Abstract
In two SIDS autopsy cases, in situ hybridization with biotin-labeled DNA probes was used to demonstrate a specific cytomegalovirus (CMV) infection in paraffin-embedded tissue sections. This technique represents a rapid, specific, and highly sensitive tool for the detection of CMV infections and is recommended for routine examination in other suspected viral infections, particularly in cases connected with SIDS.
摘要
在两例婴儿猝死综合征（SIDS）尸检病例中，采用生物素标记的DNA探针原位杂交技术，在石蜡包埋的组织切片中证实了一种特异性巨细胞病毒（CMV）感染。该技术是检测CMV感染的一种快速、特异且高度灵敏的工具，推荐用于其他疑似病毒感染的常规检查，尤其是与婴儿猝死综合征相关的病例。
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