Pekar-Zlotin Marina, Melcer Yaakov, Levinsohn-Tavor Orna, Tovbin Josef, Vaknin Zvi, Maymon Ron
Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Isr Med Assoc J. 2017 Mar;19(3):168-171.
Growing evidence suggests that cesarean scar pregnancy (CSP) and morbidly adherent placenta (MAP) may represent a continuum of the same disease.
To investigate and compare the prior risk factors in women with either CSP or MAP.
The study included 33 women diagnosed with CSP in our department between 2006 and 2014. For each CSP case, two pregnant patients with MAP were matched for hospitalization date from delivery ward records, constituting the control group.
In both groups, maternal age, parity, and previous early and late abortions were similar. The rate of conception by assisted reproductive technologies was 9% in both groups. Although the number of previous cesarean sections was statistically different between CSP versus MAP (2.0 ± 1.0 vs. 1.0 ± 1.0, respectively, P = 0.006), the leading indication of previous cesarean section was breech presentation in both groups (28.1% and 27.8%, respectively, P > 0.05).
CSP and MAP share similar prior risk factors. Due to high morbidity in both diseases, further research is needed toward reducing the known etiological factors contributing to the growing number of both complications.
越来越多的证据表明,剖宫产瘢痕妊娠(CSP)和胎盘植入(MAP)可能是同一种疾病的连续过程。
调查并比较CSP或MAP女性患者的既往危险因素。
本研究纳入了2006年至2014年间在我科诊断为CSP的33名女性患者。对于每例CSP病例,从分娩病房记录中选取两名与CSP患者住院日期匹配的MAP孕妇作为对照组。
两组患者的产妇年龄、产次以及既往早期和晚期流产情况相似。两组通过辅助生殖技术受孕的比例均为9%。虽然CSP组与MAP组既往剖宫产次数在统计学上存在差异(分别为2.0±1.0次和1.0±1.0次,P=0.006),但两组既往剖宫产的主要指征均为臀位(分别为28.1%和27.8%,P>0.05)。
CSP和MAP具有相似的既往危险因素。由于这两种疾病的发病率都很高,因此需要进一步研究以减少导致这两种并发症数量不断增加的已知病因因素。