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赫维兹泥对手部骨关节炎患者的疗效评估:一项随机、对照、单盲随访研究。

Evaluation of the Effect of Hévíz Mud in Patients with Hand Osteoarthritis: A Randomized, Controlled, Single-Blind Follow-Up Study.

作者信息

Gyarmati Noémi, Kulisch Ágota, Németh András, Bergmann Annamária, Horváth József, Mándó Zsuzsanna, Matán Ágnes, Szakál Erika, Sasné Péter Tímea, Szántó Dóra, Bender Tamás

机构信息

St. Andrew Hospital for Rheumatic Diseases, Hévíz, Hungary.

NK Medicor Ltd, Keszthely, Hungary.

出版信息

Isr Med Assoc J. 2017 Mar;19(3):177-182.

Abstract

BACKGROUND

Heat therapy is one of the most popular non-pharmacological treatments for osteoarthritis of the hand.

OBJECTIVES

To investigate the therapeutic and chemical effects of Hévíz mud on patients with hand osteoarthritis.

METHODS

We randomly assigned 47 patients with mild-to-moderate hand osteoarthritis to two groups. Patients in group 1 (n=23) received Hévíz mud applied directly to both hands, whereas patients in group 2 (n=24) also received mud to both hands, but nylon gloves separated the skin from the mud. Patients in both groups underwent five 20 minute treatment sessions per week for 3 weeks. The temperature of the mud was 42°C. Outcome measures were Visual Analogue Scale (VAS) scores, hand grip strength, the number of swollen and tender joints of the hand, the duration of morning joint stiffness, Health Assessment Questionnaire score, and EuroQoL Group 5-Dimension Self-Report Questionnaire score. The study parameters were evaluated at baseline, immediately after treatment, and after 16 weeks.

RESULTS

Both groups showed improvement in nearly all assessed parameters at the end of treatment and at 16 weeks from the start of treatment. At the week 16 follow-up visit, the patient group directly treated with mud showed significantly better improvement in VAS for II and IV parameters and in swollen joint count in both hands compared to the nylon glove-mud group.

CONCLUSIONS

Hévíz mud therapy significantly improved objective and subjective parameters in patients with hand osteoarthritis and had a beneficial effect on the patients' quality of life. Further studies are required to evaluate the chemical effects of the mud.

摘要

背景

热疗法是手部骨关节炎最常用的非药物治疗方法之一。

目的

研究赫维兹泥对手部骨关节炎患者的治疗效果和化学作用。

方法

我们将47例轻至中度手部骨关节炎患者随机分为两组。第1组(n = 23)患者双手直接涂抹赫维兹泥,而第2组(n = 24)患者双手也涂抹泥,但用尼龙手套隔开皮肤与泥。两组患者每周接受5次,每次20分钟的治疗,共治疗3周。泥的温度为42°C。观察指标包括视觉模拟评分(VAS)、握力、手部肿胀和压痛关节数、晨僵持续时间、健康评估问卷评分以及欧洲五维健康量表自评问卷评分。在基线、治疗结束后及治疗16周后对研究参数进行评估。

结果

两组患者在治疗结束时和治疗开始后16周时,几乎所有评估参数均有改善。在第16周的随访中,与尼龙手套 - 泥组相比,直接用泥治疗的患者组在II和IV参数的VAS评分以及双手肿胀关节计数方面改善更为显著。

结论

赫维兹泥疗法显著改善了手部骨关节炎患者的客观和主观参数,并对患者的生活质量产生了有益影响。需要进一步研究来评估泥的化学作用。

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