Chocarro-Ruiz Blanca, Fernández-Gavela Adrián, Herranz Sonia, Lechuga Laura M
Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, The Barcelona Institute of Science and Technology and CIBER-BBN, Campus UAB, Ed-ICN2, 08193 Bellaterra, Barcelona, Spain.
Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, The Barcelona Institute of Science and Technology and CIBER-BBN, Campus UAB, Ed-ICN2, 08193 Bellaterra, Barcelona, Spain.
Curr Opin Biotechnol. 2017 Jun;45:175-183. doi: 10.1016/j.copbio.2017.03.016. Epub 2017 Apr 28.
The field of environmental monitoring has experienced a substantial progress in the last years but still the on-site control of contaminants is an elusive problem. In addition, the growing number of pollutant sources is accompanied by an increasing need of having efficient early warning systems. Several years ago biosensor devices emerged as promising environmental monitoring tools, but their level of miniaturization and their fully operation outside the laboratory prevented their use on-site. In the last period, nanophotonic biosensors based on evanescent sensing have emerged as an outstanding choice for portable point-of-care diagnosis thanks to their capability, among others, of miniaturization, multiplexing, label-free detection and integration in lab-on-chip platforms. This review covers the most relevant nanophotonic biosensors which have been proposed (including interferometric waveguides, grating-couplers, microcavity resonators, photonic crystals and localized surface plasmon resonance sensors) and their recent application for environmental surveillance.
在过去几年中,环境监测领域取得了显著进展,但污染物的现场控制仍是一个难以解决的问题。此外,污染物源数量的不断增加,使得对高效预警系统的需求也日益增长。几年前,生物传感器设备作为有前景的环境监测工具出现,但它们的小型化程度以及在实验室外的完全运行能力阻碍了其在现场的使用。最近,基于倏逝传感的纳米光子生物传感器因其具有小型化、多路复用、无标记检测以及集成到芯片实验室平台等能力,成为便携式即时诊断的出色选择。本综述涵盖了已提出的最相关的纳米光子生物传感器(包括干涉波导、光栅耦合器、微腔谐振器、光子晶体和局域表面等离子体共振传感器)及其在环境监测中的最新应用。