Tomita Masaki, Ichiki Nobuhiko, Ayabe Takanori, Tanaka Hiroyuki, Kataoka Hiroaki, Nakamura Kunihide
Department of Thoracic and Breast Surgery, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, Japan.
Section of Oncopathology and Regenerative Biology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Miyazaki,Japan.
J Surg Case Rep. 2017 Apr 4;2017(4):rjx071. doi: 10.1093/jscr/rjx071. eCollection 2017 Apr.
Thymic epithelial tumors occur in 1-5% of patients with multiple endocrine neoplasia type 1 (MEN 1). Majority of these thymic epithelial tumors are thymic carcinoids and patients with thymoma in MEN 1 is rare. Furthermore, thymoma with neuroendocrine differentiation was also rarely reported. Herein, we report a 68-year-old man having type B3 thymoma with neuroendocrine differentiation in MEN 1 and to the best of our knowledge this is the first such case ever reported.
胸腺上皮肿瘤发生于1% - 5%的1型多发性内分泌腺瘤病（MEN 1）患者中。这些胸腺上皮肿瘤大多数是胸腺类癌，而MEN 1患者中患胸腺瘤的情况罕见。此外，具有神经内分泌分化的胸腺瘤也鲜有报道。在此，我们报告一名68岁男性，患有MEN 1相关的具有神经内分泌分化的B3型胸腺瘤，据我们所知，这是首例此类病例报道。
