Samra José A, Hagood Nancy L, Summer Andrea, Medina Marco T, Holden Kenton R
1 Department of Pediatrics, National Autonomous University of Honduras Hospital Escuela, Tegucigalpa, Honduras.
2 College of Medicine, Medical University of South Carolina, Charleston, SC, USA.
J Child Neurol. 2017 Jul;32(8):712-716. doi: 10.1177/0883073817701879. Epub 2017 May 1.
The first case of Chikungunya virus in Honduras was identified in 2014. The virus has spread widely across Honduras via the Aedes aegypti mosquito, leading to an outbreak of Chikungunya virus (CHIKV) in 2015 that significantly impacted children. A retrospective chart review of 235 children diagnosed with CHIKV and admitted to the National Autonomous University of Honduras Hospital Escuela (Hospital Escuela) in Tegucigalpa, Honduras, was accomplished with patients who were assessed for clinical features and neurologic complications. Of 235 children admitted to Hospital Escuela with CHIKV, the majority had symptoms of fever, generalized erythematous rash, and irritability. Fourteen percent had clinical arthritis. Ten percent of patients had seizures. Six percent had meningoencephalitis. There were 2 childhood deaths during the course of this study, one from meningoencephalitis and another from myocarditis. Chikungunya virus can cause severe complications in children, the majority of which impact the central nervous system.
2014年，洪都拉斯确诊首例基孔肯雅病毒感染病例。该病毒通过埃及伊蚊在洪都拉斯广泛传播，导致2015年基孔肯雅病毒（CHIKV）爆发，对儿童造成了严重影响。对235名被诊断为感染基孔肯雅病毒并入住洪都拉斯特古西加尔巴国立自治大学医学院医院（埃斯库埃拉医院）的儿童进行了回顾性病历审查，评估了这些患者的临床特征和神经系统并发症。在入住埃斯库埃拉医院的235名感染基孔肯雅病毒的儿童中，大多数有发热、全身性红斑疹和易怒症状。14%的儿童出现临床关节炎。10%的患者发生癫痫。6%的患者患有脑膜脑炎。在本研究过程中有2名儿童死亡，一名死于脑膜脑炎，另一名死于心肌炎。基孔肯雅病毒可在儿童中引起严重并发症，其中大多数影响中枢神经系统。
