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慢性疼痛患者血小板中[3H]丙咪嗪结合位点减少。

[3H]imipramine binding sites are decreased in platelets of chronic pain patients.

作者信息

Magni G, Andreoli F, Arduino C, Arsié D, Ceccherelli F, Ambrosio F, Eandi M

机构信息

Department of Psychiatry, University of Padua School of Medicine, Italy.

出版信息

Clin Neuropharmacol. 1987 Apr;10(2):175-7. doi: 10.1097/00002826-198704000-00008.

DOI:10.1097/00002826-198704000-00008
PMID:2846165
Abstract

Tritiated imipramine binding to whole platelets was measured in 16 chronic pain patients not suffering from major depression and in a control group. Maximum binding was significantly lower in chronic pain patients than in the control group, whereas the binding affinity was not significantly different.

摘要

在16名未患重度抑郁症的慢性疼痛患者及一个对照组中，对氚标记的丙咪嗪与全血血小板的结合情况进行了测定。慢性疼痛患者的最大结合量显著低于对照组，而结合亲和力无显著差异。

相似文献

1
[3H]imipramine binding sites are decreased in platelets of chronic pain patients.慢性疼痛患者血小板中[3H]丙咪嗪结合位点减少。
Clin Neuropharmacol. 1987 Apr;10(2):175-7. doi: 10.1097/00002826-198704000-00008.
2
[3H] imipramine binding sites are decreased in platelets of chronic pain patients.慢性疼痛患者血小板中[3H]丙咪嗪结合位点减少。
Acta Psychiatr Scand. 1987 Jan;75(1):108-10. doi: 10.1111/j.1600-0447.1987.tb02760.x.
3
Platelet 3H-imipramine binding in psychogenic pain patients.心因性疼痛患者血小板的3H-丙咪嗪结合情况。
Psychiatry Res. 1988 Nov;26(2):149-56. doi: 10.1016/0165-1781(88)90069-8.
4
Human platelets possess multiple [3H]imipramine binding sites.人类血小板拥有多个[3H]丙咪嗪结合位点。
Eur J Pharmacol. 1984 Nov 27;106(3):669-72. doi: 10.1016/0014-2999(84)90078-5.
5
High-affinity 3H-imipramine binding sites: a possible state-dependent marker for major depression.高亲和力3H-丙咪嗪结合位点：一种可能的重度抑郁症状态依赖性标志物。
Psychiatry Res. 1988 Feb;23(2):229-37. doi: 10.1016/0165-1781(88)90013-3.
6
Marked reduction in the number of platelet-tritiated imipramine binding sites in geriatric depression.老年抑郁症患者血小板中氚标记的丙咪嗪结合位点数量显著减少。
Arch Gen Psychiatry. 1988 Oct;45(10):919-23. doi: 10.1001/archpsyc.1988.01800340045006.
7
Solubilization and assay of [3H]imipramine binding sites from human platelets.人血小板中[3H]丙咪嗪结合位点的增溶及测定
Eur J Pharmacol. 1983 Jan 21;86(3-4):353-9. doi: 10.1016/0014-2999(83)90184-x.
8
Imipramine binding in depressed patients with psychogenic pain.患有心因性疼痛的抑郁症患者体内的丙咪嗪结合情况。
Psychiatry Res. 1990 Apr;32(1):29-34. doi: 10.1016/0165-1781(90)90132-o.
9
Tritiated imipramine binding sites are decreased in platelets of untreated depressed patients.
Science. 1980 Jul 11;209(4453):303-5. doi: 10.1126/science.7384806.
10
Electroconvulsive shock therapy and maximum binding of platelet tritiated imipramine binding in depression.
Arch Gen Psychiatry. 1986 Oct;43(10):949-52. doi: 10.1001/archpsyc.1986.01800100039006.

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