慢性疼痛患者血小板中[3H]丙咪嗪结合位点减少。

[3H] imipramine binding sites are decreased in platelets of chronic pain patients.

作者信息

Magni G, Andreoli F, Arduino C, Arsie D, Ceccherelli F, Ambrosio F, Eandi M

出版信息

Acta Psychiatr Scand. 1987 Jan;75(1):108-10. doi: 10.1111/j.1600-0447.1987.tb02760.x.

DOI:10.1111/j.1600-0447.1987.tb02760.x

Abstract

Tritiated imipramine binding to whole platelets was measured in sixteen chronic pain patients not suffering from major depression and in a control group. Maximum binding was significantly lower in chronic pain patients than in the control group, whereas the binding affinity was not significantly different.

摘要

在16名未患重度抑郁症的慢性疼痛患者及一个对照组中，测定了氚化丙咪嗪与全血血小板的结合情况。慢性疼痛患者的最大结合量显著低于对照组，而结合亲和力无显著差异。