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具有超分子刚果红的单壁碳纳米管分散体——复合物的性质及相互作用机制

Dispersion of single-wall carbon nanotubes with supramolecular Congo red - properties of the complexes and mechanism of the interaction.

作者信息

Jagusiak Anna, Piekarska Barbara, Pańczyk Tomasz, Jemioła-Rzemińska Małgorzata, Bielańska Elżbieta, Stopa Barbara, Zemanek Grzegorz, Rybarska Janina, Roterman Irena, Konieczny Leszek

机构信息

Chair of Medical Biochemistry, Faculty of Medicine, Jagiellonian University Medical College, Kopernika 7, Kraków 31-034, Poland.

Institute of Catalysis and Surface Chemistry, Polish Academy of Science, Niezapominajek 8, Kraków 30-239, Poland.

出版信息

Beilstein J Nanotechnol. 2017 Mar 16;8:636-648. doi: 10.3762/bjnano.8.68. eCollection 2017.

DOI:10.3762/bjnano.8.68
PMID:28462065
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5372747/
Abstract

A method of dispersion of single-wall carbon nanotubes (SWNTs) in aqueous media using Congo red (CR) is proposed. Nanotubes covered with CR constitute the high capacity system that provides the possibility of binding and targeted delivery of different drugs, which can intercalate into the supramolecular, ribbon-like CR structure. The study revealed the presence of strong interactions between CR and the surface of SWNTs. The aim of the study was to explain the mechanism of this interaction. The interaction of CR and carbon nanotubes was studied using spectral analysis of the SWNT-CR complex, dynamic light scattering (DLS), differential scanning calorimetry (DSC) and microscopic methods: atomic force microscopy (AFM), transmission (TEM), scanning (SEM) and optical microscopy. The results indicate that the binding of supramolecular CR structures to the surface of the nanotubes is based on the "face to face stacking". CR molecules attached directly to the surface of the nanotubes can bind further, parallel-oriented molecules and form supramolecular and protruding structures. This explains the high CR binding capacity of carbon nanotubes. The presented system - containing SWNTs covered with CR - offers a wide range of biomedical applications.

摘要

提出了一种使用刚果红（CR）在水性介质中分散单壁碳纳米管（SWNTs）的方法。覆盖有CR的纳米管构成了高容量系统，该系统提供了结合和靶向递送不同药物的可能性，这些药物可以插入超分子带状CR结构中。研究揭示了CR与SWNTs表面之间存在强相互作用。该研究的目的是解释这种相互作用的机制。使用SWNT-CR复合物的光谱分析、动态光散射（DLS）、差示扫描量热法（DSC）以及显微镜方法：原子力显微镜（AFM）、透射电子显微镜（TEM）、扫描电子显微镜（SEM）和光学显微镜对CR与碳纳米管的相互作用进行了研究。结果表明，超分子CR结构与纳米管表面的结合基于“面对面堆叠”。直接附着在纳米管表面的CR分子可以进一步结合平行取向的分子并形成超分子突出结构。这解释了碳纳米管对CR的高结合能力。所提出的包含覆盖有CR的SWNTs的系统具有广泛的生物医学应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/a31fdf7dc77c/Beilstein_J_Nanotechnol-08-636-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/25f6a7e66fd5/Beilstein_J_Nanotechnol-08-636-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/b89165b205d2/Beilstein_J_Nanotechnol-08-636-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/d095ea63e293/Beilstein_J_Nanotechnol-08-636-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/6d7b62b31de7/Beilstein_J_Nanotechnol-08-636-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/b656c47a0fca/Beilstein_J_Nanotechnol-08-636-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/9ed55f5fba47/Beilstein_J_Nanotechnol-08-636-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/7180094cf1a9/Beilstein_J_Nanotechnol-08-636-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/bff3d37b10e1/Beilstein_J_Nanotechnol-08-636-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/94b7cbc6c6d0/Beilstein_J_Nanotechnol-08-636-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/e5df9ffbe6a2/Beilstein_J_Nanotechnol-08-636-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/a31fdf7dc77c/Beilstein_J_Nanotechnol-08-636-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/25f6a7e66fd5/Beilstein_J_Nanotechnol-08-636-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/a4fbdae6cc13/Beilstein_J_Nanotechnol-08-636-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/b89165b205d2/Beilstein_J_Nanotechnol-08-636-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/d095ea63e293/Beilstein_J_Nanotechnol-08-636-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/6d7b62b31de7/Beilstein_J_Nanotechnol-08-636-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/b656c47a0fca/Beilstein_J_Nanotechnol-08-636-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/9ed55f5fba47/Beilstein_J_Nanotechnol-08-636-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/7180094cf1a9/Beilstein_J_Nanotechnol-08-636-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/bff3d37b10e1/Beilstein_J_Nanotechnol-08-636-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/94b7cbc6c6d0/Beilstein_J_Nanotechnol-08-636-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/e5df9ffbe6a2/Beilstein_J_Nanotechnol-08-636-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb4/5372747/a31fdf7dc77c/Beilstein_J_Nanotechnol-08-636-g013.jpg

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本文引用的文献

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2
Adsorption of methylene blue and Congo red from aqueous solution by activated carbon and carbon nanotubes.活性炭和碳纳米管从水溶液中吸附亚甲基蓝和刚果红。
Water Sci Technol. 2013;68(10):2240-8. doi: 10.2166/wst.2013.487.
3
Carbon nanotubes for delivery of small molecule drugs.碳纳米管用于小分子药物的递送。
Adv Drug Deliv Rev. 2013 Dec;65(15):1964-2015. doi: 10.1016/j.addr.2013.08.005. Epub 2013 Aug 14.
4
Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities.多功能纳米粒子：添加靶向和成像功能的成本与效益。
Science. 2012 Nov 16;338(6109):903-10. doi: 10.1126/science.1226338.
5
Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes.化学功能化碳纳米管穿过质膜的转位机制。
Biomaterials. 2012 Apr;33(11):3334-43. doi: 10.1016/j.biomaterials.2012.01.024. Epub 2012 Jan 30.
6
CNT loading into cationic cholesterol suspensions show improved DNA binding and serum stability and ability to internalize into cancer cells.将 CNT 载入阳离子胆固醇悬浮液中，可提高 DNA 结合能力和血清稳定性，并增强其进入癌细胞的内化能力。
Nanotechnology. 2012 Feb 17;23(6):065101. doi: 10.1088/0957-4484/23/6/065101.
7
Influence of the electric field on supramolecular structure and properties of amyloid-specific reagent Congo red.电场对淀粉样蛋白特异性试剂刚果红的超分子结构和性质的影响。
Eur Biophys J. 2011 Oct;40(10):1187-96. doi: 10.1007/s00249-011-0750-z. Epub 2011 Sep 24.
8
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Biochim Biophys Acta. 2010 Aug;1806(1):29-35. doi: 10.1016/j.bbcan.2010.02.004. Epub 2010 Feb 26.
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Targeted delivery and controlled release of doxorubicin to cancer cells using modified single wall carbon nanotubes.使用改性单壁碳纳米管将阿霉素靶向递送至癌细胞并实现其控释
Biomaterials. 2009 Oct;30(30):6041-7. doi: 10.1016/j.biomaterials.2009.07.025. Epub 2009 Jul 29.
10
Functionalized single-walled carbon nanotubes as rationally designed vehicles for tumor-targeted drug delivery.功能化单壁碳纳米管作为用于肿瘤靶向药物递送的合理设计载体。
J Am Chem Soc. 2008 Dec 10;130(49):16778-85. doi: 10.1021/ja805570f.