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饮食与心血管疾病:经典和新兴心血管危险因素中食物和营养素的作用。

Diet and Cardiovascular Disease: Effects of Foods and Nutrients in Classical and Emerging Cardiovascular Risk Factors.

机构信息

Cardiovascular Program-ICCC, Research Institute-Hospital Santa Creu i Sant Pau, Barcelona, Spain.

CIBERCV Instituto de Salud Carlos III, Madrid, Spain.

出版信息

Curr Med Chem. 2019;26(19):3639-3651. doi: 10.2174/0929867324666170428103206.

DOI:10.2174/0929867324666170428103206
PMID:28462707
Abstract

Cardiovascular diseases (CVD) are the leading cause of mortality worldwide. Diet comprises a mixture of food compounds that has an influence on human health. The relationship between diet and health is extremely complex and strategies to delay or prevent chronic diseases such as CVD are of utmost interest because chronic diseases and more concretely CVD are still the leading cause of death and disability worldwide. In this mini-review, we aimed to summarize the current knowledge about the principal diet components that potentially influence CVD initiation and progression. Current research refers to the Mediterranean dietary pattern, rich in fruits and vegetables, as the most cardioprotective, because of its high concentration of bioactive compounds such as unsaturated fatty acids, polyphenols, fiber, phytosterols, vitamins and minerals, which exert antioxidant, anti-inflammatory and antithrombotic effects contributing to the delay of CVD initiation and progression.

摘要

心血管疾病(CVD)是全球范围内主要的死亡原因。饮食由多种食物成分组成,这些成分会对人体健康产生影响。饮食与健康之间的关系极其复杂,因此寻找能够延缓或预防 CVD 等慢性疾病的策略非常重要,因为慢性疾病,更具体地说是 CVD,仍然是全球范围内导致死亡和残疾的主要原因。在这篇迷你综述中,我们旨在总结当前关于可能影响 CVD 发生和发展的主要饮食成分的知识。目前的研究认为富含水果和蔬菜的地中海饮食模式最具心脏保护作用,因为其富含生物活性化合物,如不饱和脂肪酸、多酚、纤维、植物固醇、维生素和矿物质,这些化合物具有抗氧化、抗炎和抗血栓形成的作用,有助于延缓 CVD 的发生和发展。

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