Spencer E, Araya M, Sandino A M, Pacheco I, Brunser O
Institute of Nutrition and Food Technology, Universidad de Chile, Santiago.
Epidemiol Infect. 1988 Oct;101(2):425-36. doi: 10.1017/s0950268800054388.
Faecal excretion of enteropathogens was studied in newborns in their first week of life. Rotavirus was investigated in 225 neonates, of whom 107 belonged to the low socio-economic stratum (SES) and 118 to the high SES. Half of each group were delivered by caesarean section. Rotavirus was detected in 10 infants (4.4%). Eight of them had been in the same ward and excreted the same viral electrophoretype. Enteropathogenic bacteria were isolated from 8 out of 57 (14.0%) newborns. Positive cultures were equally distributed by SES and route of delivery. Giardia lamblia was the only parasite detected, in one infant (2.6%) of the high SES. None of the children developed symptoms. Faecal excretion of enteropathogens ended spontaneously within a week in all cases. It is suggested that the lack of symptomatology and the spontaneous termination of the faecal excretion are related to immaturity of the small intestinal mucosa, that does not allow the completion of the steps that must take place during a successful infectious event.
对出生第一周的新生儿肠道病原体的粪便排泄情况进行了研究。对225名新生儿进行了轮状病毒调查，其中107名属于社会经济地位较低阶层（SES），118名属于社会经济地位较高阶层。每组各有一半通过剖宫产分娩。在10名婴儿（4.4%）中检测到轮状病毒。其中8名婴儿在同一病房，并排出相同的病毒电泳型。从57名新生儿中的8名（14.0%）分离出肠道致病菌。阳性培养物在社会经济地位和分娩途径方面分布均匀。蓝氏贾第鞭毛虫是唯一检测到的寄生虫，在一名社会经济地位较高阶层的婴儿中发现（2.6%）。所有儿童均未出现症状。所有病例中，肠道病原体的粪便排泄在一周内自行停止。有人认为，缺乏症状以及粪便排泄的自发终止与小肠黏膜不成熟有关，这使得成功感染过程中必须发生的步骤无法完成。
