Young R H, Scully R E
Department of Pathology, Harvard Medical School, Boston, Massachusetts.
Int J Gynecol Pathol. 1988;7(3):197-211. doi: 10.1097/00004347-198809000-00001.
Three women, 51-69 years of age with carcinomas of the urinary bladder or ureter, had ovarian tumors of identical cell types 2 to 7 years apart. In two cases the tumors were transitional-cell carcinomas and in the third case, signet-ring-cell carcinomas. It was difficult in the cases of transitional-cell carcinoma to determine whether the ovarian tumors were metastatic or independent primary tumors. Consideration of a variety of features of our two cases and of four similar cases reported in the literature led us to the conclusion that the ovarian tumors were probably metastatic in one case, probably primary in two cases, and of unknown nature in three cases, but some degree of doubt existed in all the cases. The signet-ring-cell tumor in the ovary had the typical features of a Krukenberg tumor. Four of 11 women with signet-ring-cell carcinomas of the bladder have had ovarian metastases.
三名年龄在51至69岁之间患有膀胱癌或输尿管癌的女性，在相隔2至7年的时间里出现了相同细胞类型的卵巢肿瘤。其中两例肿瘤为移行细胞癌，第三例为印戒细胞癌。在移行细胞癌的病例中，很难确定卵巢肿瘤是转移性的还是独立的原发性肿瘤。综合考虑我们这两例以及文献中报道的四例类似病例的各种特征后，我们得出结论：其中一例卵巢肿瘤可能是转移性的，两例可能是原发性的，三例性质不明，但所有病例都存在一定程度的疑问。卵巢中的印戒细胞瘤具有典型的库肯勃瘤特征。11名患有膀胱印戒细胞癌的女性中有4人出现了卵巢转移。
