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[婴儿肠道微生物群的组成及其影响因素]

[The composition of gut microbiota in infant and its influencing factors].

作者信息

Liu W, Feng J Q, Fan A Q, Zhang M J, Zhou Y L, Liu T, Xu Y J

机构信息

Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, China.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2017 May 6;51(5):453-456. doi: 10.3760/cma.j.issn.0253-9624.2017.05.017.

Abstract

Gut microbiota provide enzymes and additional biochemical metabolic pathways for the host, which together with the host genome and the external environment, influence the body function. The composition of gut microbiota in infant is closely related to health in later life. However, it is influenced by many factors, including delivery mode, feeding pattern, prenatal diet, pregnancy psychology and antepartum antibiotic treatment. Vaginal delivery and breastfeeding is beneficial for shaping gut microbiota, while cesarean section and formula feeding would reduce the amount of gut dominant bacteria. In addition, inappropriate diet during pregnancy, prenatal stress and antepartum antibiotic treatment alters bacterial colonization of the gut in infant.

摘要

肠道微生物群为宿主提供酶和其他生化代谢途径,这些与宿主基因组和外部环境一起影响身体功能。婴儿肠道微生物群的组成与晚年健康密切相关。然而,它受到许多因素的影响,包括分娩方式、喂养模式、产前饮食、孕期心理和产前抗生素治疗。阴道分娩和母乳喂养有利于塑造肠道微生物群,而剖宫产和配方奶喂养会减少肠道优势菌的数量。此外,孕期饮食不当、产前压力和产前抗生素治疗会改变婴儿肠道中的细菌定植。

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