Protection of microvasculature in rat brain against late radiation injury by gammaphos.
作者信息
Plotnikova E D, Levitman M K, Shaposhnikova V V, Koshevoj J V, Eidus L K
机构信息
Institute of Biological Physics, Academy of Sciences of the USSR, Pushchino, Moscow Region.
出版信息
Int J Radiat Oncol Biol Phys. 1988 Nov;15(5):1197-201. doi: 10.1016/0360-3016(88)90204-0.
PMID:2846482
Abstract
The ability of the radioprotector gammaphos to modify the development of late vascular changes in rat brain after local irradiation with 25 Gy was investigated by means of angiographic method. A protective effect was seen against late vascular abnormalities. It is suggested that a causative relationship exists between vascular abnormalities, brain necrosis, and radiation mortality after irradiation with moderate doses.
摘要
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