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[经γ-磷(gammaphos)防护的长期照射后大脑微循环的变化]

[Change in cerebral microcirculation at long-term periods following irradiation with protection by gammaphos].

作者信息

Plotnikova E D, Levitman M Kh, Shaposhnikova V V, Eĭdus L Kh

出版信息

Med Radiol (Mosk). 1983 Jul;28(7):19-22.

PMID:6308381
Abstract

A study was made of the influence of prophylactic administration of gammaphos (300 mg/kg) on radiation alterations in the system of cerebral microcirculation of rats in a long-term period following local irradiation of doses of 40-60 Gy. It has been shown that the number of animals with severe vascular injuries and the degree of these injuries lessen. A computerized analysis has shown that gammaphos administration weakens a decrease in the mean number of vessels and an increase in their average size caused by irradiation.

摘要

研究了预防性给予γ-磷(300毫克/千克)对大鼠脑微循环系统在局部照射40 - 60 Gy剂量后的长期辐射改变的影响。结果表明,出现严重血管损伤的动物数量及其损伤程度均有所减轻。计算机分析显示,给予γ-磷可减弱由辐射引起的血管平均数量减少和血管平均大小增加的现象。

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