Elisei Walter, Brandimarte Giovanni, Tursi Antonio
Unit of Gastroenterology, ASL Roma 6, Albano Laziale, Rome, Italy.
Division of Internal Medicine and Gastroenterology, "Cristo Re" Hospital, Rome, Italy.
Minerva Med. 2017 Oct;108(5):448-463. doi: 10.23736/S0026-4806.17.05201-6. Epub 2017 May 2.
The incidence of diverticulosis and diverticular disease (DD) of the colon, including acute diverticulitis, is increasing worldwide, and becoming a significant burden on national health systems in terms of direct and indirect costs. Thus, significant efforts are now being focused to identify the correct therapeutic approach to treat symptomatic patients and to prevent diverticulitis. Fiber, non-absorbable antibiotics, 5-aminosalicylic acid and probioticsare currently being investigated in this way. Unfortunately, current evidences on the effectiveness of some medical treatment in preventing acute diverticulitis recurrence are still lacking. The effectiveness and the future perspectives of these treatments are discussed herein.
结肠憩室病及憩室病(DD),包括急性憩室炎的发病率在全球范围内呈上升趋势,在直接和间接成本方面给国家卫生系统带来了沉重负担。因此,目前正投入大量精力来确定治疗有症状患者和预防憩室炎的正确治疗方法。目前正在通过这种方式对纤维、不可吸收抗生素、5-氨基水杨酸和益生菌进行研究。不幸的是,目前仍缺乏关于某些药物治疗预防急性憩室炎复发有效性的证据。本文将讨论这些治疗方法的有效性及未来前景。