Fierro-Benitez R, Cazar R, Stanbury J B, Rodriguez P, Garces F, Fierro-Renoy F, Estrella E
National Polytechnical School and Central University, Quito, Ecuador.
J Endocrinol Invest. 1988 May;11(5):327-35. doi: 10.1007/BF03349050.
The results of tests of intellectual and psychomotor performance and school performance in a group of school children from a rural impoverished and iodine deficient Andean community whose mothers received injections of iodinated oil prior to the end of the first trimester of pregnancy have been compared with results in children from a neighboring comparable community whose mothers had received no iodinated oil. Subjects between ages 8 and 15 were studied. Statistically significant differences were not observed between the two groups in tests of intellectual function, but children of mothers who had received iodinated oil performed better on tests of psychomotor maturation. The group whose mothers had received oil performed distinctly better when assessed in terms of school drop-out rates, grades achieved, grades repeated, and in overall performance as judged by teacher notes in school records. Performance of both groups on standard tests of intellectual and psychomotor function was lower than standard scores. This may be a result of social and cultural deprivation, the general malnutrition prevailing in the region or other unidentified factors. The improved scoring and school performance exhibited by the children of mothers who received iodinated oil underlines the importance of prophylaxis with iodine in iodine deficient regions as one important contributor to community development.
对来自安第斯山区一个农村贫困且缺碘社区的一组学龄儿童进行了智力、心理运动能力测试以及学业成绩测试,这些儿童的母亲在怀孕头三个月末之前接受了碘化油注射。将其测试结果与来自邻近可比社区、其母亲未接受碘化油注射的儿童的测试结果进行了比较。研究对象为8至15岁的儿童。在智力功能测试中,两组之间未观察到统计学上的显著差异,但母亲接受过碘化油注射的儿童在心理运动成熟度测试中表现更好。当根据辍学率、取得的成绩、留级情况以及学校记录中教师评语所判断的总体表现来评估时,母亲接受过碘化油注射的那组表现明显更好。两组在智力和心理运动功能标准测试中的表现均低于标准分数。这可能是社会和文化剥夺、该地区普遍存在的总体营养不良或其他不明因素造成的。母亲接受过碘化油注射的儿童在评分和学业成绩方面的改善突出了在缺碘地区进行碘预防作为社区发展的一个重要因素的重要性。