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需要紧急转运至医院的重大创伤患者的院前通知:一项系统综述。

Prehospital notification for major trauma patients requiring emergency hospital transport: A systematic review.

作者信息

Synnot Anneliese, Karlsson Adrian, Brichko Lisa, Chee Melissa, Fitzgerald Mark, Misra Mahesh C, Howard Teresa, Mathew Joseph, Rotter Thomas, Fiander Michelle, Gruen Russell L, Gupta Amit, Dharap Satish, Fahey Madonna, Stephenson Michael, O'Reilly Gerard, Cameron Peter, Mitra Biswadev

机构信息

Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.

Cochrane Consumers and Communication, Centre for Health Communication and Participation, School of Psychology and Public Health, La Trobe University, Melbourne, Australia.

出版信息

J Evid Based Med. 2017 Aug;10(3):212-221. doi: 10.1111/jebm.12256.

Abstract

OBJECTIVE

This systematic review aimed to determine the effect of prehospital notification systems for major trauma patients on overall (<30 days) and early (<24 hours) mortality, hospital reception, and trauma team presence (or equivalent) on arrival, time to critical interventions, and length of hospital stay.

METHODS

Experimental and observational studies of prehospital notification compared with no notification or another type of notification in major trauma patients requiring emergency transport were included. Risk of bias was assessed using the Cochrane ACROBAT-NRSI tool. A narrative synthesis was conducted and evidence quality rated using the GRADE criteria.

RESULTS

Three observational studies of 72,423 major trauma patients were included. All were conducted in high-income countries in hospitals with established trauma services, with two studies undertaking retrospective analysis of registry data. Two studies reported overall mortality, one demonstrating a reduction in mortality; (adjusted odds ratio (OR) 0.61, 95% confidence interval (CI) 0.39 to 0.94, 72,073 participants); and the other demonstrating a nonsignificant change (OR 0.61, 95% CI 0.23 to 1.64, 81 participants). The quality of this evidence was rated as very low.

CONCLUSION

Limited research on the topic constrains conclusive evidence on the effect of prehospital notification on patient-centered outcomes after severe trauma. Composite interventions that combine prehospital notification with effective actions on arrival to hospital such as trauma bay availability, trauma team presence, and early access to definitive management may provide more robust evidence towards benefits of early interventions during trauma reception and resuscitation.

摘要

目的

本系统评价旨在确定针对重大创伤患者的院前通知系统对总体(<30天)和早期(<24小时)死亡率、医院接收情况、到达时创伤团队在场(或同等情况)、关键干预时间以及住院时间的影响。

方法

纳入了对需要紧急转运的重大创伤患者进行院前通知与不通知或另一种通知类型比较的实验性和观察性研究。使用Cochrane ACROBAT-NRSI工具评估偏倚风险。进行了叙述性综合分析,并使用GRADE标准对证据质量进行评级。

结果

纳入了三项针对72423名重大创伤患者的观察性研究。所有研究均在高收入国家设有成熟创伤服务的医院中进行,两项研究对登记数据进行了回顾性分析。两项研究报告了总体死亡率,一项显示死亡率降低(调整后的优势比(OR)为0.61,95%置信区间(CI)为0.39至0.94,72073名参与者);另一项显示无显著变化(OR为0.61,95%CI为0.23至1.64,81名参与者)。该证据的质量被评为极低。

结论

关于该主题的研究有限,限制了关于院前通知对严重创伤后以患者为中心的结局影响的确凿证据。将院前通知与到达医院后有效行动(如创伤病房可用性、创伤团队在场以及早期获得确定性治疗)相结合的综合干预措施,可能会为创伤接收和复苏期间早期干预的益处提供更有力的证据。

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