Veer Manik, Abdulmassih Rasha, Como James, Min Zaw, Bhanot Nitin
Department of Internal Medicine, Allegheny General Hospital, Pittsburgh, PA, USA.
Division of Infectious Disease, Allegheny General Hospital, Pittsburgh, PA, USA.
Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12716. Epub 2017 Jul 17.
Adenovirus (AdV) infections in transplant recipients may cause invasive disease. We present a case of granulomatous interstitial nephritis secondary to AdV infection in a renal transplant recipient that was initially interpreted as acute graft rejection on histopathology. Specific testing based on clinical suspicion, however, aided in making an accurate diagnosis. We present a retrospective review of all cases of AdV infection in renal transplant recipients to date, and analyze outcomes based on different treatment modalities for this disease.
移植受者的腺病毒（AdV）感染可能会导致侵袭性疾病。我们报告了一例肾移植受者因AdV感染继发肉芽肿性间质性肾炎的病例，该病例在组织病理学上最初被误诊为急性移植排斥反应。然而，基于临床怀疑进行的特异性检测有助于做出准确诊断。我们对迄今为止肾移植受者中所有AdV感染病例进行了回顾性分析，并根据针对该疾病的不同治疗方式分析了预后情况。
