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自由生活的肠杆菌24613:全基因组序列与代谢谱分析

Free-Living Enterobacterium 24613: Complete Genome Sequence and Metabolic Profiling.

作者信息

Snopková Kateřina, Sedlář Karel, Bosák Juraj, Chaloupková Eva, Sedláček Ivo, Provazník Ivo, Šmajs David

机构信息

Department of Biology, Masaryk University, Brno, Czech Republic.

Department of Biomedical Engineering, Brno University of Technology, Brno, Czech Republic.

出版信息

Evol Bioinform Online. 2017 Mar 30;13:1176934317700863. doi: 10.1177/1176934317700863. eCollection 2017.

DOI:10.1177/1176934317700863
PMID:28469381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5395255/
Abstract

is one of the few species that belongs to the group of atypical hydrogen sulfide-producing enterobacteria. Unlike other members of this closely related group, is not associated with any known host and has been reported as a free-living bacterium. Whole genome sequencing and metabolic fingerprinting confirmed the phylogenetic position of inside the group of atypical HS producers. Genomic data have revealed that 24613 has limited pathogenic potential, although there are signs of genome decay. Although the lack of specific virulence factors and no association with a host species suggest a free-living style, the signs of genome decay suggest a process of adaptation to an as-yet-unknown host.

摘要

是少数属于非典型产硫化氢肠道杆菌群体的物种之一。与这个密切相关群体的其他成员不同,它与任何已知宿主都没有关联,并且已被报道为一种自由生活的细菌。全基因组测序和代谢指纹分析证实了其在非典型HS产生菌群体中的系统发育位置。基因组数据显示,尽管有基因组衰退的迹象,但24613的致病潜力有限。虽然缺乏特定的毒力因子且与宿主物种没有关联表明其自由生活方式,但基因组衰退的迹象表明它正在适应一个尚未知晓的宿主。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b20b/5395255/cad3b71001c8/10.1177_1176934317700863-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b20b/5395255/d29bfc5dfde4/10.1177_1176934317700863-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b20b/5395255/cad3b71001c8/10.1177_1176934317700863-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b20b/5395255/d29bfc5dfde4/10.1177_1176934317700863-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b20b/5395255/cad3b71001c8/10.1177_1176934317700863-fig2.jpg

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Genome Announc. 2015 Jul 9;3(4):e00740-15. doi: 10.1128/genomeA.00740-15.
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