Graham Emily, Rao Krishna, Cinti Sandro
Department of Pediatrics, University of Michigan, Ann Arbor, MI, USA.
Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Infect Dis (Auckl). 2017 Apr 7;10:1179916117701736. doi: 10.1177/1179916117701736. eCollection 2017.
Few studies exist to guide the treatment approach to intra-abdominal abscesses in Crohn disease, which can include antimicrobials alone or in conjunction with percutaneous drainage or surgery. The primary aim of this study is to review outcomes from different treatment approaches to intra-abdominal abscess in Crohn disease.
Medical records were reviewed for patients admitted to the University of Michigan health care system with Crohn disease and intra-abdominal abscess over a 4-year period. Outcomes were compared among medical and interventional approaches. The χ test was used to test for statistical significance.
Of the 33 patients included, 13 were in the medical group and 20 were in the interventional group. Abscess recurrence/nonresolution occurred in 31% of patients in the medical group and 25% of patients in the interventional group ( = .7).
In this study, there was no significant difference in outcome between medical and interventional therapy for intra-abdominal abscess in Crohn disease.
关于指导克罗恩病腹腔内脓肿治疗方法的研究较少，其治疗方法可包括单独使用抗菌药物或联合经皮引流或手术。本研究的主要目的是回顾克罗恩病腹腔内脓肿不同治疗方法的疗效。
回顾了密歇根大学医疗系统在4年期间收治的患有克罗恩病和腹腔内脓肿患者的病历。比较了药物治疗和介入治疗方法的疗效。采用χ检验来检验统计学显著性。
纳入的33例患者中，13例在药物治疗组，20例在介入治疗组。药物治疗组31%的患者出现脓肿复发/未消退，介入治疗组25%的患者出现这种情况（P = 0.7）。
在本研究中，克罗恩病腹腔内脓肿的药物治疗和介入治疗疗效无显著差异。
