Vashakidze R P, Chelidze M G, Mamulashvili N A, Kalandarishvili K G, Tsalkalamanidze N V
Mol Biol (Mosk). 1988 May-Jun;22(3):700-5.
Binding of simple homopolymeric sequences to Drosophila melanogaster nuclear proteins has been studied. Proteins with Mr 65-72 kDa have been found, which specifically bind to synthetic poly[d(T-G)].poly[d(C-A)], as well as to D. melanogaster DNA containing a block of poly[d(T-G)].poly[d(C-A) 40 b.p. in length. It has been shown, that these proteins bind only to poly[d(T-G).poly[d(C-A)] and not to other types of simple sequences, for example poly[d(G-A)].poly[d(T-C)] and poly[d(A-T)].
已对简单同聚序列与黑腹果蝇核蛋白的结合进行了研究。发现了分子量为65 - 72 kDa的蛋白质，它们能特异性结合合成的聚[d(T - G)]·聚[d(C - A)]，以及含有一段长度为40个碱基对的聚[d(T - G)]·聚[d(C - A)]的黑腹果蝇DNA。结果表明，这些蛋白质仅与聚[d(T - G)]·聚[d(C - A)]结合，而不与其他类型的简单序列结合，例如聚[d(G - A)]·聚[d(T - C)]和聚[d(A - T)]。
