纳米比亚新城疫病毒的首次基因特征分析：一种新型VIIk亚基因型的鉴定。
First genetic characterization of newcastle disease viruses from Namibia: identification of a novel VIIk subgenotype.
作者信息
Molini Umberto, Aikukutu Gottlieb, Khaiseb Siegfried, Cattoli Giovanni, Dundon William G
机构信息
Central Veterinary Laboratory (CVL), 24 Goethe Street, P. Box 18137, Windhoek, Namibia.
Animal Production and Health Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, Wagramer Strasse 5, P.O. Box 100, 1400, Vienna, Austria.
出版信息
Arch Virol. 2017 Aug;162(8):2427-2431. doi: 10.1007/s00705-017-3389-y. Epub 2017 May 3.
The complete sequences of the fusion (F) protein genes of six Newcastle disease virus (NDV) isolates from backyard poultry in Namibia in 2016 have been determined. The F gene cleavage site motif for all of the isolates was RRQKRF, indicating that the viruses are virulent. A phylogenetic analysis using the full F gene sequence revealed that the viruses belong to a novel subgenotype, VIIk. This is the first genetic characterization of NDV isolates from Namibia, and the findings have important implications for Newcastle disease management and control in the region.
已确定2016年来自纳米比亚后院家禽的6株新城疫病毒（NDV）分离株融合（F）蛋白基因的完整序列。所有分离株的F基因裂解位点基序均为RRQKRF，表明这些病毒具有致病性。使用完整F基因序列进行的系统发育分析表明，这些病毒属于一个新的亚基因型，VIIk。这是纳米比亚NDV分离株的首次基因特征分析，研究结果对该地区新城疫的管理和控制具有重要意义。
Zotero 插件