modlAMP：用于抗菌肽的Python

modlAMP: Python for antimicrobial peptides.

作者信息

Müller Alex T, Gabernet Gisela, Hiss Jan A, Schneider Gisbert

机构信息

Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology (ETH), CH-8093 Zurich, Switzerland.

出版信息

Bioinformatics. 2017 Sep 1;33(17):2753-2755. doi: 10.1093/bioinformatics/btx285.

DOI:10.1093/bioinformatics/btx285

PMID:28472272

Abstract

SUMMARY

We have implemented the lecular esign aboratory's nti icrobial eptides package ( ), a Python-based software package for the design, classification and visual representation of peptide data. modlAMP offers functions for molecular descriptor calculation and the retrieval of amino acid sequences from public or local sequence databases, and provides instant access to precompiled datasets for machine learning. The package also contains methods for the analysis and representation of circular dichroism spectra.

AVAILABILITY AND IMPLEMENTATION

The modlAMP Python package is available under the BSD license from URL http://doi.org/10.5905/ethz-1007-72 or via pip from the Python Package Index (PyPI).

CONTACT

gisbert.schneider@pharma.ethz.ch.

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

我们已经实现了分子设计实验室的抗菌肽软件包（modlAMP），这是一个基于Python的软件包，用于肽数据的设计、分类和可视化表示。modlAMP提供了用于分子描述符计算以及从公共或本地序列数据库检索氨基酸序列的功能，并为机器学习提供对预编译数据集的即时访问。该软件包还包含用于分析和表示圆二色光谱的方法。