Sharpe Louise, McDonald Sarah, Correia Helen, Raue Patrick J, Meade Tanya, Nicholas Michael, Arean Patricia
School of Psychology, University of Sydney, Sydney, Australia.
Department of Psychology, Macquarie University, Sydney, Australia.
BMC Psychiatry. 2017 May 4;17(1):166. doi: 10.1186/s12888-017-1334-y.
Multi-morbidity in older adults is commonly associated with depressed mood. Similarly, subjective reports of pain are also associated with both physical illness and increased depressive symptoms. However, whether pain independently contributes to the experience of depression in older people with multi-morbidity has not been studied.
In this study, participants were 1281 consecutive older adults presenting to one of 19 primary care services in Australia (recruitment rate = 75%). Participants were asked to indicate the presence of a number of common chronic illnesses, to rate their current pain severity and to complete the Geriatric Depression Scale.
Results confirmed that the number of medical illnesses reported was strongly associated with depressive symptoms. Twenty-six percent of participants with multi-morbidity scored in the clinical range for depressive symptoms in comparison to 15% of participants with no illnesses or a single illness. In regression analyses, the presence of chronic pain (t = 5.969, p < 0.0005), diabetes (t = 4.309, p < 0.0005), respiratory (t = 3.720, p < 0.0005) or neurological illness (t = 2.701, p = 0.007) were all independent contributors to depressive symptoms. Even when controlling for each individual illness, and the overall number of illnesses (t = 2.207, p = 0.028), pain severity remained an independent predictor of depressed mood (F change = 28.866, p < 0.0005, t = 5.373, p < 0.0005).
Physicians should consider screening for mood problems amongst those with multi-morbidity, particularly those who experience pain.
老年人的多种疾病通常与情绪低落有关。同样,疼痛的主观报告也与身体疾病和抑郁症状增加有关。然而,疼痛是否独立导致患有多种疾病的老年人出现抑郁症状尚未得到研究。
在本研究中,参与者为连续就诊于澳大利亚19家初级保健机构之一的1281名老年人(招募率=75%)。参与者被要求指出是否患有多种常见慢性病,对当前疼痛严重程度进行评分,并完成老年抑郁量表。
结果证实,报告的疾病数量与抑郁症状密切相关。患有多种疾病的参与者中有26%在抑郁症状临床范围内得分,而无疾病或仅患一种疾病的参与者中这一比例为15%。在回归分析中,慢性疼痛(t=5.969,p<0.0005)、糖尿病(t=4.309,p<0.0005)、呼吸系统疾病(t=3.720,p<0.0005)或神经系统疾病(t=2.701,p=0.007)均是抑郁症状的独立影响因素。即使对每种疾病以及疾病总数进行控制(t=2.207,p=0.028),疼痛严重程度仍是抑郁情绪的独立预测因素(F变化=28.866,p<0.0005,t=5.373,p<0.0005)。
医生应考虑对患有多种疾病的患者,尤其是经历疼痛的患者进行情绪问题筛查。