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立陶宛头痛疾病的患病率、负担及其对公共卫生和政策的影响:一项在“欧洲之光”项目内基于人群的研究。

Prevalence and burden of headache disorders in Lithuania and their public-health and policy implications: a population-based study within the Eurolight Project.

作者信息

Rastenytė Daiva, Mickevičienė Dalia, Stovner Lars Jacob, Thomas Hallie, Andrée Colette, Steiner Timothy J

机构信息

Lithuanian University of Health Sciences, Kaunas, Lithuania.

Department of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, NTNU Norwegian University of Science and Technology, Trondheim, NO-7941, Norway.

出版信息

J Headache Pain. 2017 Dec;18(1):53. doi: 10.1186/s10194-017-0759-5. Epub 2017 May 4.

Abstract

BACKGROUND

The Eurolight project assessed the impact of headache disorders in ten EU countries, using the same structured questionnaire but varying sampling methods. In Lithuania, sample selection employed methods in line with consensus recommendations for population-based burden-of-headache studies.

METHODS

The survey was cross-sectional. We identified, from the Residents' Register Service, a sample of inhabitants of Kaunas city and surrounding Kaunas region reflecting age (in the range 18-65 years), gender and rural/urban distributions of Lithuania. Medical students called unannounced at their homes and conducted face-to-face interviews employing a structured questionnaire.

RESULTS

Of 1137 people in the pre-identified sample, 573 (male 237 [41.4%], female 336 [58.6%]; mean age 40.9 ± 13.8 years) completed interviews (participation proportion: 50.4%). Gender-adjusted 1-year prevalences were: any headache 74.7%; migraine 18.8%; tension-type headache (TTH) 42.2%; all headache on ≥15 days/month 8.6%; probable medication-overuse headache (pMOH) 3.2%. Migraine (OR: 3.6) and pMOH (OR: 2.9) were associated with female gender. All headache types except TTH were associated with significantly diminished quality of life. Migraine caused a mean 4.5% loss in paid worktime per affected male and 3.5% per affected female. Lost per-person times due to TTH were much less, but to pMOH and other headache on ≥15 days/month much higher. Among the entire workforce, lost productivity to migraine was estimated at 0.7%, to TTH 0.3% and to pMOH or other headache on ≥15 days/month 0.5%. The total of 1.5% may translate directly into lost GDP. Alternative calculations based on headache yesterday (with little recall error) produced, for all headache, a corroborating 1.7%. Similar losses from household work would also drain the nation's economy. Our findings were comparable to those from earlier studies using similar methods in Russia and Georgia.

CONCLUSIONS

The multiple burdens from headache in Lithuania indicate substantial ill-health and unmet need for health care. The heavy burdens on individuals are matched by heavy economic burden. Of particular concern is the high prevalence of headache on ≥15 days/month, seen also in Russia and Georgia. Health policy in Lithuania must heed WHO's advice that effective treatment of headache, clearly desirable for its health benefits, is also expected to be cost-saving.

摘要

背景

“欧洲之光”项目评估了头痛疾病在10个欧盟国家的影响,使用的是相同的结构化问卷,但抽样方法各异。在立陶宛,样本选择采用的方法符合基于人群的头痛负担研究的共识建议。

方法

该调查为横断面研究。我们从居民登记服务处确定了考纳斯市及周边考纳斯地区的居民样本,该样本反映了立陶宛的年龄(18至65岁)、性别以及农村/城市分布情况。医学生不事先通知就登门拜访,并使用结构化问卷进行面对面访谈。

结果

在预先确定的1137人中,573人(男性237人[41.4%],女性336人[58.6%];平均年龄40.9±13.8岁)完成了访谈(参与比例:50.4%)。经性别调整的1年患病率为:任何头痛74.7%;偏头痛18.8%;紧张型头痛(TTH)42.2%;每月≥15天的所有头痛8.6%;可能的药物过量使用性头痛(pMOH)3.2%。偏头痛(比值比:3.6)和pMOH(比值比:2.9)与女性性别相关。除TTH外,所有头痛类型均与生活质量显著下降相关。偏头痛导致每位受影响男性的带薪工作时间平均损失4.5%,每位受影响女性损失3.5%。TTH导致的人均误工时间要少得多,但pMOH和每月≥15天的其他头痛导致的误工时间要高得多。在整个劳动力群体中,偏头痛导致的生产力损失估计为0.7%,TTH为0.3%,pMOH或每月≥15天的其他头痛为0.5%。这1.5%的总和可能直接转化为国内生产总值的损失。基于昨天头痛情况(回忆误差很小)的替代计算得出,所有头痛的损失率为1.7%,与之相符。家务劳动方面的类似损失也会消耗国家经济。我们的研究结果与俄罗斯和格鲁吉亚早期使用类似方法的研究结果相当。

结论

立陶宛头痛带来的多重负担表明存在严重的健康问题以及未满足的医疗需求。个人承受的沉重负担伴随着沉重的经济负担。特别令人担忧的是每月≥15天头痛的高患病率,在俄罗斯和格鲁吉亚也有发现。立陶宛的卫生政策必须听从世界卫生组织的建议,即有效治疗头痛,显然因其对健康有益,预计也会节省成本。

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