Laboratorio de Vacunología y Constatación, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México.
Laboratorio de Microbiología Molecular, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México.
Transbound Emerg Dis. 2018 Feb;65(1):267-271. doi: 10.1111/tbed.12641. Epub 2017 May 4.
The genus Pestivirus within Flaviviridae is comprised of four recognized species, namely, bovine viral diarrhoea virus 1 (BVDV-1), bovine viral diarrhoea virus 2 (BVDV-2), border disease virus (BDV) and classical swine fever virus (CSFV). BDV, while primarily infecting sheep and goats, has also been reported in cattle and wild animals. Infections of sheep and goats result in economic loss due to abortions and the birth of persistently infected animals that have poor production and reduced life expectancy. In this study, we report the detection of BDV in cattle serum collected as part of pestivirus surveillance programme from six regions of Mexico, where a 67.1% of BVDV seroprevalence was calculated previously. Phylogenetic analyses based on comparison of the 5'UTR region typed the Mexican strains as BDV-1. Border disease (BD) is listed as an exotic disease in Mexico, and the origin of BDV found in these cattle is unclear. This is the first identification of BDV in Mexican cattle.
黄病毒科中的瘟病毒属包含四个已被确认的种，即牛病毒性腹泻病毒 1 型（BVDV-1）、牛病毒性腹泻病毒 2 型（BVDV-2）、边界病病毒（BDV）和古典猪瘟病毒（CSFV）。BDV 主要感染绵羊和山羊，但也有在牛和野生动物中报告的病例。绵羊和山羊的感染会导致流产和持续性感染动物的出生，这些动物的生产性能差，预期寿命缩短，从而造成经济损失。在本研究中，我们报告了在墨西哥六个地区的瘟病毒监测计划中采集的牛血清中检测到 BDV 的情况，此前该地区的 BVDV 血清阳性率为 67.1%。基于 5'UTR 区域的比较进行的系统进化分析将墨西哥株分型为 BDV-1。边界病（BD）在墨西哥被列为外来疾病，这些牛中发现的 BDV 的来源尚不清楚。这是墨西哥牛中首次鉴定出 BDV。
