Jitsukawa K, Sueki H, Sato S, Anzai T
Division of Dermatology, Japanese Red Cross Medical Center, Tokyo, Japan.
Am J Dermatopathol. 1987 Apr;9(2):99-108. doi: 10.1097/00000372-198704000-00003.
Electron-microscopic studies of two typical lesions of eccrine spiradenoma were performed to correlate ultrastructure and histopathology. The salient ultramorphological features of the parenchyma were an adenoid cystic organization composed of epithelial, myoepithelial, and nonepithelial cell types, and the presence of intracytoplasmic luminae within the epithelial cells. There were no indications that the parenchyma was secretorily active. The stroma ramified through the parenchyma, occupying extensive areas and forming tenuous septa of the loose connective tissue in which blood vessels and nerve fibers were embedded. Profiles of cystoid spaces resulting from invagination of stroma into the parenchyma were frequently encountered. Based on our observations, eccrine spiradenoma appears to differentiate toward ductal structures of eccrine sweat apparatus.
对小汗腺螺旋腺瘤的两种典型病变进行了电子显微镜研究，以关联超微结构和组织病理学。实质的显著超微形态学特征是由上皮细胞、肌上皮细胞和非上皮细胞类型组成的腺样囊性结构，以及上皮细胞内存在胞质内管腔。没有迹象表明实质具有分泌活性。间质在实质中分支，占据广泛区域并形成疏松结缔组织的细薄间隔，血管和神经纤维嵌入其中。经常遇到间质内陷进入实质形成的囊样间隙轮廓。基于我们的观察，小汗腺螺旋腺瘤似乎朝着小汗腺分泌装置的导管结构分化。
