Seifert H W
Dermatologica. 1983;166(1):1-9.
2 cases of eccrine spiradenoma were analyzed histologically and electron microscopically. In neither case true glandular structures could be found. On the submicroscopic level, 'lumina', as seen by light microscopic method, were found to be stroma islands containing fibrillar material, or cavities probably formed by cell decay. In case 2, submicroscopic examination revealed a considerable degree of cell and tissue alteration as intercellular edema, cellular shrinkage and phagocytic phenomenons. A striking finding was a marked dissociation of the stroma resulting in the formation of small units which were sometimes found to be phagocytized within tumor cells. These alterations are interpreted as a sign of regressive transformation of the tumor.
对2例小汗腺螺旋腺瘤进行了组织学和电子显微镜分析。在这两例中均未发现真正的腺管结构。在亚微观水平上，光镜下所见的“管腔”被发现是含有纤维状物质的间质岛，或可能由细胞退变形成的腔隙。在病例2中，亚微观检查显示有相当程度的细胞和组织改变，如细胞间水肿、细胞皱缩和吞噬现象。一个显著的发现是间质明显分离，形成小单元，有时可发现这些小单元被肿瘤细胞吞噬。这些改变被解释为肿瘤退行性变的迹象。
