Division of Infectious Diseases, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, and.
Center for Infection Prevention and Control, Samsung Medical Center, Seoul, Republic of Korea.
Clin Infect Dis. 2017 May 15;64(suppl_2):S82-S90. doi: 10.1093/cid/cix133.
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as an important cause of healthcare-associated infection. CA-MRSA clones have replaced classic hospital MRSA clones in many countries and have shown higher potential in transmission and virulence than hospital MRSA clones. In particular, the emergence of CA-MRSA in the Asia-Pacific region is concerning owing to insufficient infection control measures in the region. The old strategies for infection prevention and control of MRSA comprised adherence to standard precaution and policy of active screening of MRSA carriers and decolonization, and it has been controversial which strategy is better in terms of outcome and cost-effectiveness. Epidemiological changes in MRSA has made the development of infection prevention strategy more complicated. Based on the literature review and the questionnaire survey, we considered infection prevention strategies for healthcare settings in the Asia-Pacific region in the era of CA-MRSA.
社区相关性耐甲氧西林金黄色葡萄球菌（CA-MRSA）已成为医源性感染的重要病因。CA-MRSA 克隆已在许多国家取代了经典的医院 MRSA 克隆，其在传播和毒力方面比医院 MRSA 克隆具有更高的潜力。特别是，由于该地区感染控制措施不足，CA-MRSA 在亚太地区的出现令人担忧。MRSA 的感染预防和控制的旧策略包括坚持标准预防和对 MRSA 携带者的主动筛查和去定植政策，哪种策略在结果和成本效益方面更好存在争议。MRSA 的流行病学变化使感染预防策略的制定更加复杂。基于文献回顾和问卷调查，我们考虑了 CA-MRSA 时代亚太地区医疗机构的感染预防策略。
